AT157702T - Alkaline phosphatase having an improved specific activity for use in indicator reagents - Google Patents

Alkaline phosphatase having an improved specific activity for use in indicator reagents

Info

Publication number
AT157702T
AT157702T AT91101338T AT91101338T AT157702T AT 157702 T AT157702 T AT 157702T AT 91101338 T AT91101338 T AT 91101338T AT 91101338 T AT91101338 T AT 91101338T AT 157702 T AT157702 T AT 157702T
Authority
AT
Austria
Prior art keywords
use
alkaline phosphatase
specific activity
improved specific
indicator reagents
Prior art date
Application number
AT91101338T
Other languages
German (de)
Inventor
Wlodzimierz Mandecki
Susan J Tomazic-Allen
Mary Ann Shallcross
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US47619990A priority Critical
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of AT157702T publication Critical patent/AT157702T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/535Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
AT91101338T 1990-02-07 1991-02-01 Alkaline phosphatase having an improved specific activity for use in indicator reagents AT157702T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US47619990A true 1990-02-07 1990-02-07

Publications (1)

Publication Number Publication Date
AT157702T true AT157702T (en) 1997-09-15

Family

ID=23890914

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91101338T AT157702T (en) 1990-02-07 1991-02-01 Alkaline phosphatase having an improved specific activity for use in indicator reagents

Country Status (7)

Country Link
EP (1) EP0441252B1 (en)
JP (1) JP2620416B2 (en)
AT (1) AT157702T (en)
AU (1) AU656313B2 (en)
CA (1) CA2035826A1 (en)
DE (2) DE69127482T2 (en)
ES (1) ES2106737T3 (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4546093A (en) * 1992-07-07 1994-01-31 Abbott Laboratories Alkaline phosphatase enzymes having improved specific activity for use in indicator reagents
US5304472A (en) * 1992-11-20 1994-04-19 Genentech, Inc. Method of controlling polypeptide production in bacterial cells
WO1994020636A1 (en) * 1993-03-09 1994-09-15 Abbott Laboratories Genetically engineered enzymes and their conjugates for diagnostic assays
AU4835693A (en) * 1993-08-13 1995-03-14 Rijksuniversiteit Te Groningen Pharmaceutical composition comprising phosphatase or a derivative thereof
CA2239686A1 (en) * 1995-12-07 1997-06-12 Recombinant Biocatalysis, Inc. Method of screening for enzyme activity
US6720014B1 (en) 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US7078035B2 (en) 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6183740B1 (en) 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US7432097B2 (en) 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
JP4812617B2 (en) 2003-02-24 2011-11-09 ニュー・イングランド・バイオラブズ・インコーポレイティッドNew England Biolabs, Inc. Overexpression of thermolabile phosphatase, purified and property analysis
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US7933639B2 (en) 2003-08-01 2011-04-26 Dexcom, Inc. System and methods for processing analyte sensor data
US7778680B2 (en) 2003-08-01 2010-08-17 Dexcom, Inc. System and methods for processing analyte sensor data
US7640048B2 (en) 2004-07-13 2009-12-29 Dexcom, Inc. Analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US20100168542A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
WO2007102842A2 (en) 2006-03-09 2007-09-13 Dexcom, Inc. Systems and methods for processing analyte sensor data
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7519408B2 (en) 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
AT480761T (en) 2003-12-05 2010-09-15 Dexcom Inc Calibration methods for a continuous analyte sensor
EP1711791B1 (en) 2003-12-09 2014-10-15 DexCom, Inc. Signal processing for continuous analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
EP1985697A1 (en) * 2007-04-27 2008-10-29 AM-Pharma B.V. Modified phosphatases
CA2715628A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
HUE030948T2 (en) 2009-05-21 2017-06-28 Basf Enzymes Llc Phytases, nucleic acids encoding them and methods for making and using them
EP2620162A1 (en) 2012-01-27 2013-07-31 Life Science Inkubator Enzyme-polymer conjugate for endotoxin detoxification
EP2814331B1 (en) * 2012-02-16 2018-12-05 Elanco US Inc. Methods and compositions for reducing the environmental impact of animal waste
JP5866715B2 (en) 2013-10-18 2016-02-17 国立大学法人九州大学 Detection method of protein detection for fusion proteins and protein
US9926544B2 (en) 2014-01-24 2018-03-27 Am-Pharma B.V. Chimeric alkaline phosphatase-like proteins

Also Published As

Publication number Publication date
DE69127482T2 (en) 1998-03-19
DE69127482D1 (en) 1997-10-09
EP0441252A3 (en) 1991-11-21
EP0441252A2 (en) 1991-08-14
JP2620416B2 (en) 1997-06-11
ES2106737T3 (en) 1997-11-16
AU7083791A (en) 1991-08-08
AU656313B2 (en) 1995-02-02
JPH04349881A (en) 1992-12-04
EP0441252B1 (en) 1997-09-03
CA2035826A1 (en) 1991-08-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee