AT153663T - Piperidines and piperazine, the effects on the zns show - Google Patents

Piperidines and piperazine, the effects on the zns show

Info

Publication number
AT153663T
AT153663T AT94114798T AT94114798T AT153663T AT 153663 T AT153663 T AT 153663T AT 94114798 T AT94114798 T AT 94114798T AT 94114798 T AT94114798 T AT 94114798T AT 153663 T AT153663 T AT 153663T
Authority
AT
Austria
Prior art keywords
piperidines
zns
piperazine
effects
show
Prior art date
Application number
AT94114798T
Other languages
German (de)
Inventor
Henning Dr Boettcher
Christoph Dr Seyfried
Gerd Bartoszyk
Hartmut Dr Greiner
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19934333254 priority Critical patent/DE4333254A1/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AT153663T publication Critical patent/AT153663T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
AT94114798T 1993-09-30 1994-09-20 Piperidines and piperazine, the effects on the zns show AT153663T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19934333254 DE4333254A1 (en) 1993-09-30 1993-09-30 Piperidines and piperazines

Publications (1)

Publication Number Publication Date
AT153663T true AT153663T (en) 1997-06-15

Family

ID=6499013

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94114798T AT153663T (en) 1993-09-30 1994-09-20 Piperidines and piperazine, the effects on the zns show

Country Status (19)

Country Link
US (1) US5532241A (en)
EP (1) EP0648767B1 (en)
JP (2) JP4065034B2 (en)
CN (1) CN1056610C (en)
AT (1) AT153663T (en)
AU (1) AU679774B2 (en)
CA (1) CA2133152C (en)
CZ (1) CZ293558B6 (en)
DE (1) DE4333254A1 (en)
DK (1) DK0648767T3 (en)
ES (1) ES2105454T3 (en)
GR (1) GR3024551T3 (en)
HU (1) HU218918B (en)
NO (1) NO306948B1 (en)
PL (1) PL178137B1 (en)
RU (1) RU2132848C1 (en)
SK (1) SK281793B6 (en)
TW (1) TW313569B (en)
ZA (1) ZA9407622B (en)

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CN102267985B (en) * 2011-06-15 2015-12-09 上海医药工业研究院 Preparation of one or the hydrochloride salt Wei Lazuo
CN102949364A (en) * 2011-08-30 2013-03-06 天津药物研究院 Sustained release tablet containing effective component hydrochloric acid vilazodone
US9505744B2 (en) 2011-11-23 2016-11-29 Assia Chemical Industries Ltd. Solid state forms of vilazodone and vilazodone hydrochloride
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US9969721B2 (en) 2012-04-12 2018-05-15 Alembic Pharmaceuticals Limited Process for the preparation of vilazodone hydrochloride and its amorphous form
US20150073148A1 (en) 2012-04-16 2015-03-12 Ranbaxy Laboratories Limited Process for the preparation of crystalline vilazodone hydrochloride
WO2013164794A1 (en) 2012-05-04 2013-11-07 Ranbaxy Laboratories Limited Crystalline forms of vilazodone hydrochloride
CN102659660B (en) * 2012-05-11 2014-07-02 杭州和泽医药科技有限公司 Preparation method and application of 3-(4-chlorobutyl)-5-cyano-1H-indole
WO2013175361A1 (en) 2012-05-24 2013-11-28 Ranbaxy Laboratories Limited Process for the preparation of vilazodone hydrochloride
US8835635B2 (en) 2012-06-05 2014-09-16 Symed Labs Limited Amorphous form of vilazodone hydrochloride substantially free of crystalline forms
WO2013182946A2 (en) * 2012-06-06 2013-12-12 Ranbaxy Laboratories Limited Process for the preparation of vilazodone hydrochloride
EP2861586A4 (en) 2012-06-13 2015-11-11 Apotex Inc Forms of vilazodone and processes for the preparation thereof
WO2014005134A2 (en) * 2012-06-29 2014-01-03 Forest Laboratories Holdings Limited 4-(2-(6-substituted-hexylidene) hydrazinyl)benzonitrile and preparation thereof
US9399630B2 (en) 2012-07-02 2016-07-26 Symed Labs Limited Process for preparing benzofuran-2-carboxamide derivatives
CN102796037B (en) * 2012-08-09 2013-11-06 成都苑东药业有限公司 3-(4-(4-substituted-piperazino)-1-butyryl)indolyl-5-formonitrile and application thereof
WO2014028473A1 (en) 2012-08-13 2014-02-20 Assia Chemical Industries Ltd. New salts of vilazodone and solid state forms thereof
WO2014040164A1 (en) 2012-09-12 2014-03-20 Apotex Pharmachem Inc. Processes for the preparation of 3-alkyl indoles
WO2014049609A2 (en) 2012-09-26 2014-04-03 Cadila Healthcare Limited Novel salts of vilazodone
WO2014061004A2 (en) 2012-10-19 2014-04-24 Ranbaxy Laboratories Limited Process for the preparation of vilazodone or pharmaceutically acceptable salt thereof
WO2014061000A1 (en) 2012-10-19 2014-04-24 Ranbaxy Laboratories Limited Process for the preparation of vilazodone or pharmaceutically acceptable salt thereof
WO2014064715A2 (en) 2012-10-22 2014-05-01 Cadila Healthcare Limited Amorphous form of vilazodone hydrochloride and process for preparing thereof
CN102977083A (en) * 2012-12-17 2013-03-20 南京海纳医药科技有限公司 New crystal form XVII of 1-(4-(5-cyanoindole-3-yl) butyl)-4-(2-carbamyl-benzofuran-5-yl)-piperazine hydrochloride and preparation method of new crystal form XVII
CN102993186B (en) * 2012-12-20 2015-11-18 北京海步国际医药科技发展有限公司 A novel piperazine derivative
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CN104098552A (en) * 2013-04-02 2014-10-15 上海医药工业研究院 Preparation method of vilazodone
WO2014178013A1 (en) 2013-04-30 2014-11-06 Ranbaxy Laboratories Limited Vilazodone impurities, process for their preparation, and their use as reference standards
IN2013MU02001A (en) 2013-06-12 2015-05-29 Lupin Limited Substantially pure vilazodone hydrochloride and a process thereof
CN103360373B (en) * 2013-07-12 2016-06-15 苏州永健生物医药有限公司 Vera oxazolone synthesis intermediates and their salts
EP2824104A1 (en) 2013-07-12 2015-01-14 Sandoz AG Process for the preparation of form III of Vilazodone hydrochloride
WO2015014256A1 (en) 2013-07-29 2015-02-05 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
WO2015019256A1 (en) 2013-08-06 2015-02-12 Ranbaxy Laboratories Limited Pharmaceutical composition of vilazodone and processes of preparation thereof
WO2015019237A1 (en) 2013-08-06 2015-02-12 Ranbaxy Laboratories Limited Pharmaceutical composition of vilazodone
EP3083589A4 (en) 2013-12-20 2017-05-24 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use thereof
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WO2016128987A1 (en) * 2015-02-13 2016-08-18 Harman Finochem Limited A process for preparation of 2-benzofurancarboxamide, 5-[4-[4-(5cyano-1h-indol-3-yl)butyl]-1-piperazinyl] free base and its hydrochloride salt
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Also Published As

Publication number Publication date
NO943616L (en) 1995-03-31
CA2133152C (en) 2005-08-30
AU679774B2 (en) 1997-07-10
HU218918B (en) 2000-12-28
PL178137B1 (en) 2000-03-31
ZA9407622B (en) 1995-05-16
EP0648767B1 (en) 1997-05-28
US5532241A (en) 1996-07-02
JPH07149762A (en) 1995-06-13
CA2133152A1 (en) 1995-03-31
DK0648767T3 (en) 1997-12-22
GR3024551T3 (en) 1997-12-31
JP2007119502A (en) 2007-05-17
DK648767T3 (en)
JP4065034B2 (en) 2008-03-19
NO306948B1 (en) 2000-01-17
DE4333254A1 (en) 1995-04-06
RU94035660A (en) 1996-07-20
ES2105454T3 (en) 1997-10-16
KR950008510A (en) 1995-04-17
RU2132848C1 (en) 1999-07-10
TW313569B (en) 1997-08-21
EP0648767A1 (en) 1995-04-19
NO943616D0 (en) 1994-09-29
SK281793B6 (en) 2001-08-06
SK118494A3 (en) 1995-05-10
HU9402806D0 (en) 1995-01-30
HUT71833A (en) 1996-02-28
CZ237094A3 (en) 1995-04-12
CZ293558B6 (en) 2004-06-16
AU7424494A (en) 1995-04-13
PL305216A1 (en) 1995-04-03
CN1106811A (en) 1995-08-16
CN1056610C (en) 2000-09-20
JP4700017B2 (en) 2011-06-15

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