AT124720B - Process for the production of water-soluble silicic acid-protein compounds. - Google Patents
Process for the production of water-soluble silicic acid-protein compounds.Info
- Publication number
- AT124720B AT124720B AT124720DA AT124720B AT 124720 B AT124720 B AT 124720B AT 124720D A AT124720D A AT 124720DA AT 124720 B AT124720 B AT 124720B
- Authority
- AT
- Austria
- Prior art keywords
- water
- production
- silicic acid
- soluble silicic
- protein compounds
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 3
- 150000001875 compounds Chemical class 0.000 title claims 2
- 239000005018 casein Substances 0.000 claims description 6
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 6
- 235000021240 caseins Nutrition 0.000 claims description 6
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 6
- 239000004115 Sodium Silicate Substances 0.000 claims description 5
- 235000019795 sodium metasilicate Nutrition 0.000 claims description 5
- 229910052911 sodium silicate Inorganic materials 0.000 claims description 5
- 230000002378 acidificating effect Effects 0.000 claims description 3
- 235000018102 proteins Nutrition 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 102000004407 Lactalbumin Human genes 0.000 description 1
- 108090000942 Lactalbumin Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silicon Compounds (AREA)
Description
<Desc/Clms Page number 1>
EMI1.1
EMI1.2
Lactalbuminat und Natrimmetasilikat für therapeutyische Zwecke mit kolloidal löslicher Kieselsäure besteht hauptsächlich darin, das durch Auflösen von Casein bzw. Laetalbuminat in einer wässerigen Lösung von Natriummetasilikat erzeugte Produkt durch Eindampfen in eine trockene Form zu bringen, ohnedassdieWasserlöslichkeitundderkolloidaleZustandderKeselsätureindemPräparateverlorengehen.
Löst man nämlich Casein bzw. Laetalbuminat unter Zusatz der erforderlichen Menge Natriunt- metasilikats in Wasser, so erhält man eine fast neutrale bis schwach saure Lösung. Dampft man diese Lösung aber auf dem Wasserbade bei 90-100" C zur Trockne, so löst sieh der sepulverte Rückstand wohl noch leidlich in heissem Wasser, die Kieselsäure hat aber den kolloidalen Zustand eingebüsst. Das zeigt sich dadurch, dass sie beim Stehen der Lösung ausflockt und sich am Boden als sandiges, knirschendes
EMI1.3
Form wertlos.
EMI1.4
mässige Verteilung der Komponenten gewährleistet ist.
Wenn man als Eiweissstoff von saurem Charakter an Stelle von Casein ein Albuminat. z. B. das aus koagiuliertemLactalbumin durch starke Natronlauge gelöste und durch verdünnte Salzsäure aus- gefällte Produkt, verwenden will, verfährt man ganz ähnlich wie bei Anwendung'von C'asein. Jedoch sind in dem Falle nur 3,5-3,7 Gewichtsteile Natriummetasilikat (Na2SiO3) auf 100 Gewichtsteile Laetalbuminat erforderlieh, um zu einem mit neutraler bis schwach saurer Reaktion in Wasser löslichen
EMI1.5
dem aus Casein und Natriummetasilikat erhaltenen ganz ähnlich.
**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.
<Desc / Clms Page number 1>
EMI1.1
EMI1.2
Lactalbuminate and sodium metasilicate for therapeutic purposes with colloidally soluble silicic acid consists mainly of evaporating the product produced by dissolving casein or laetalbuminate in an aqueous solution of sodium metasilicate into a dry form, without the water solubility and the colloidal state of the kettle acid being lost.
If one dissolves casein or laetalbuminate with the addition of the required amount of sodium metasilicate in water, an almost neutral to weakly acidic solution is obtained. If this solution is steamed to dryness on a water bath at 90-100 "C, the powdered residue will probably still dissolve reasonably in hot water, but the silica has lost its colloidal state. This is shown by the fact that it does so when the solution stands flocculates and appears on the ground as sandy, crunchy
EMI1.3
Form worthless.
EMI1.4
moderate distribution of the components is guaranteed.
If one uses an albuminate instead of casein as a protein of acidic character. z. If, for example, you want to use the product dissolved from coagulated lactalbumin by strong sodium hydroxide solution and precipitated by dilute hydrochloric acid, the procedure is very similar to the application of casein. However, in this case only 3.5-3.7 parts by weight of sodium metasilicate (Na2SiO3) per 100 parts by weight of metalbuminate are required in order to produce a water-soluble solution with a neutral to weakly acidic reaction
EMI1.5
very similar to that obtained from casein and sodium metasilicate.
** WARNING ** End of DESC field may overlap beginning of CLMS **.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT124720T | 1927-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT124720B true AT124720B (en) | 1931-10-10 |
Family
ID=3633979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT124720D AT124720B (en) | 1927-01-27 | 1927-01-27 | Process for the production of water-soluble silicic acid-protein compounds. |
Country Status (1)
| Country | Link |
|---|---|
| AT (1) | AT124720B (en) |
-
1927
- 1927-01-27 AT AT124720D patent/AT124720B/en active
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