AT100447T - 19-nor-vitamin-d derivatives. - Google Patents

19-nor-vitamin-d derivatives.

Info

Publication number
AT100447T
AT100447T AT90302521T AT90302521T AT100447T AT 100447 T AT100447 T AT 100447T AT 90302521 T AT90302521 T AT 90302521T AT 90302521 T AT90302521 T AT 90302521T AT 100447 T AT100447 T AT 100447T
Authority
AT
Austria
Prior art keywords
vitamin
derivatives
Prior art date
Application number
AT90302521T
Other languages
German (de)
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Rafal R Sicinski
Jean Martin Prahl
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US32103089A priority Critical
Priority to US07/481,354 priority patent/US5237110A/en
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of AT100447T publication Critical patent/AT100447T/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26982778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT100447(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
AT90302521T 1989-03-09 1990-03-09 19-nor-vitamin-d derivatives. AT100447T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US32103089A true 1989-03-09 1989-03-09
US07/481,354 US5237110A (en) 1989-03-09 1990-02-16 19-nor-vitamin d compounds

Publications (1)

Publication Number Publication Date
AT100447T true AT100447T (en) 1994-02-15

Family

ID=26982778

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90302521T AT100447T (en) 1989-03-09 1990-03-09 19-nor-vitamin-d derivatives.

Country Status (8)

Country Link
EP (1) EP0387077B1 (en)
CN (1) CN1033857C (en)
AT (1) AT100447T (en)
DE (3) DE122006000018I2 (en)
ES (1) ES2062334T3 (en)
IE (1) IE64526B1 (en)
NL (1) NL300228I1 (en)
NZ (1) NZ232734A (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
AU649057B2 (en) * 1990-08-24 1994-05-12 Wisconsin Alumni Research Foundation Methods and compositions containing vitamin D compounds for improvement of skin conditions
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
DK0474517T3 (en) * 1990-09-07 1999-08-02 Wisconsin Alumni Res Found Hitherto unknown use of alpha-hydroxylated-19-nor-vitamin D-
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DE69213844T2 (en) * 1991-07-05 1997-04-10 Duphar Int Res Vitamin D derivative, process for its production and intermediates therefor
CA2129120A1 (en) * 1992-01-29 1993-08-05 Joyce C. Knutson 1.alpha.-hydroxy-24-epi-vitamin d4
DE4220757A1 (en) * 1992-06-24 1994-01-05 Schering Ag Derivatives in the vitamin D series with modifications in the 20-position, process for their preparation, intermediates for this process, pharmaceutical preparations containing these derivatives and their use in the manufacture of medicaments
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (en) * 1992-11-20 1996-01-01 Hoffmann La Roche
DE69400495T2 (en) * 1993-04-05 1997-04-30 Wisconsin Alumni Res Found 19-nor-vitamin D3 compound with a substituent in the 2nd position
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
DE69433220T2 (en) * 1993-07-09 2004-08-19 Laboratoire Theramex New structural vitamin d derivatives
DE69503394T2 (en) * 1994-01-20 1999-03-11 Duphar Int Res Vitamin D derivatives and process for their preparation
WO1996016035A1 (en) * 1994-11-21 1996-05-30 Wisconsin Alumni Research Foundation 18,19-dinor-vitamin d compounds
DK0717034T3 (en) * 1994-12-14 1999-10-18 Duphar Int Res Vitamin D compounds and methods for preparing these compounds
US5597815A (en) * 1995-07-13 1997-01-28 Wisconsin Alumni Research Foundation Prevention of hyperphosphatemia in kidney disorder patients
AT290869T (en) 1995-12-28 2005-04-15 Chugai Pharmaceutical Co Ltd Use of vitamin d derivatives for the production of a medicament for the treatment of molecular tumor metastase
US6869940B2 (en) 1995-12-28 2005-03-22 Chugai Seiyaku Kabushiki Kaisha Malignant tumor metastasis inhibitors
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
US6316642B1 (en) 1997-03-17 2001-11-13 Wisconsin Alumni Research Foundation 26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US6306844B1 (en) 1997-03-17 2001-10-23 Wisconsin Alumni Research Foundation Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
US5945410A (en) * 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US6392071B1 (en) 1997-03-17 2002-05-21 Wisconsin Alumni: Research Foundation 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
JP3276375B2 (en) * 1997-05-23 2002-04-22 バジリア ファルマスーチカ アーゲー Cyclohexanediol derivative
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US6114317A (en) 1998-05-21 2000-09-05 Wisconsin Alumni Research Foundation Method of locking 1α-OH of vitamin D compounds in axial orientation
EP1286962B1 (en) 2000-05-31 2008-06-25 Wisconsin Alumni Research Foundation 2-ethyl and 2-ethylidene-19-nor-vitamin d compounds
BRPI0409194A (en) 2003-04-10 2006-04-11 Wisconsin Alumni Res Found compounds, pharmaceutical composition and method of treatment of metabolic bone disease, psoriasis, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer, autoimmune disease, inflammatory bowel disease and augmentation bone strength
US6894037B2 (en) 2003-07-03 2005-05-17 Wisconsin Alumni Research Foundation 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US7713951B2 (en) 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
CN101223135A (en) * 2005-07-18 2008-07-16 特瓦制药工业有限公司 Preparation of paricalcitol and crystalline forms thereof
NZ571896A (en) 2006-04-05 2011-09-30 Wisconsin Alumni Res Found 1-Alpha.-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and use thereof
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US7491712B1 (en) 2007-12-10 2009-02-17 Formosa Laboratories, Inc. Process for preparation of paricalcitol and intermediates thereof
WO2010009879A2 (en) 2008-07-22 2010-01-28 Azad Pharmaceutical Ingredients Ag Methods for producing paricalcitol
PL216135B1 (en) 2009-08-07 2014-03-31 Inst Farmaceutyczny New synthons and application thereof for the preparation of 19-nor vitamin D derivatives
EP2545940A1 (en) 2011-07-14 2013-01-16 hameln rds gmbh Parenteral compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448726A (en) * 1983-05-11 1984-05-15 Wisconsin Alumni Research Foundation Ring A- and triene-modified vitamin D compounds
DE3590021C2 (en) * 1984-01-30 1992-09-10 Wisconsin Alumni Res Found Alpha-hydroxyvitamin D derivative and medicinal product containing the same
US4555364A (en) * 1984-11-01 1985-11-26 Wisconsin Alumni Research Foundation Method for preparing 1-hydroxyvitamin D compounds
CA1314872C (en) * 1986-04-25 1993-03-23 Toshio Nishizawa Fluorine derivatives of vitamin d _and process for producing the same

Also Published As

Publication number Publication date
IE900840L (en) 1990-09-09
ES2062334T3 (en) 1994-12-16
IE64526B1 (en) 1995-08-09
CN1033857C (en) 1997-01-22
DE122006000018I2 (en) 2008-05-08
EP0387077B1 (en) 1994-01-19
NZ232734A (en) 1991-11-26
NL300228I1 (en) 2006-06-01
DE122006000018I1 (en) 2006-06-29
EP0387077A1 (en) 1990-09-12
CN1046155A (en) 1990-10-17
DE69006052D1 (en) 1994-03-03
DE69006052T2 (en) 1994-05-05

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Legal Events

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