AR209575A1 - Un procedimiento para preparar nuevos derivados sustituidos de 5-,6-,7-u8-(3-amino-2-oxisustituido)-propoxi-3,4-dihidrocarbostirilo y de 5-,6-,7-u8-(3-amino-2-hidroxi)propoxi -3,4-dihidrocarbostirilo - Google Patents
Un procedimiento para preparar nuevos derivados sustituidos de 5-,6-,7-u8-(3-amino-2-oxisustituido)-propoxi-3,4-dihidrocarbostirilo y de 5-,6-,7-u8-(3-amino-2-hidroxi)propoxi -3,4-dihidrocarbostiriloInfo
- Publication number
- AR209575A1 AR209575A1 AR246548A AR24654873A AR209575A1 AR 209575 A1 AR209575 A1 AR 209575A1 AR 246548 A AR246548 A AR 246548A AR 24654873 A AR24654873 A AR 24654873A AR 209575 A1 AR209575 A1 AR 209575A1
- Authority
- AR
- Argentina
- Prior art keywords
- amino
- oxisustitido
- dihydrocarbostirile
- dihidrocarbostirilo
- propoxi
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47037181A JPS517672B2 (da) | 1972-04-13 | 1972-04-13 | |
| JP47037182A JPS48103590A (da) | 1972-04-13 | 1972-04-13 | |
| JP9255772A JPS5324431B2 (da) | 1972-09-14 | 1972-09-14 | |
| JP47092560A JPS5246231B2 (da) | 1972-09-14 | 1972-09-14 | |
| JP47092558A JPS5241268B2 (da) | 1972-09-14 | 1972-09-14 | |
| JP47120953A JPS5229745B2 (da) | 1972-04-13 | 1972-12-02 | |
| JP47125858A JPS5239036B2 (da) | 1972-04-13 | 1972-12-14 | |
| JP47128972A JPS5241269B2 (da) | 1972-04-13 | 1972-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR209575A1 true AR209575A1 (es) | 1977-05-13 |
Family
ID=27572212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR246548A AR209575A1 (es) | 1972-04-13 | 1973-02-12 | Un procedimiento para preparar nuevos derivados sustituidos de 5-,6-,7-u8-(3-amino-2-oxisustituido)-propoxi-3,4-dihidrocarbostirilo y de 5-,6-,7-u8-(3-amino-2-hidroxi)propoxi -3,4-dihidrocarbostirilo |
Country Status (17)
| Country | Link |
|---|---|
| JP (5) | JPS517672B2 (da) |
| AR (1) | AR209575A1 (da) |
| AU (1) | AU475964B2 (da) |
| BE (1) | BE794669A (da) |
| CA (1) | CA1025447A (da) |
| CH (1) | CH575929A5 (da) |
| DD (2) | DD112446A5 (da) |
| DE (1) | DE2302027C2 (da) |
| DK (1) | DK141603B (da) |
| FI (1) | FI53703C (da) |
| FR (1) | FR2179715B1 (da) |
| GB (2) | GB1424572A (da) |
| HK (1) | HK19481A (da) |
| NL (1) | NL158176B (da) |
| NO (1) | NO140589C (da) |
| SE (1) | SE380018B (da) |
| YU (1) | YU41187B (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5082218A (da) * | 1973-11-10 | 1975-07-03 | ||
| US4022784A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives |
| US4137331A (en) | 1974-06-19 | 1979-01-30 | Sandoz Ltd. | 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones |
| JPS516971A (en) * | 1974-07-08 | 1976-01-20 | Otsuka Pharma Co Ltd | Nitoro 3*44 jihidorokarubosuchirirujudotaino seizoho |
| JPS5129486A (en) * | 1974-09-02 | 1976-03-12 | Otsuka Pharma Co Ltd | * 33 arukiruamino 22 hidorokishi * purohokishi 3 44 jihidorokarubosuchirirujudotai no seizoho |
| JPS5148674A (en) * | 1974-10-17 | 1976-04-26 | Otsuka Pharma Co Ltd | 3 44 jihidorokarubosuchirirujudotaino seizoho |
| JPS5152180A (ja) * | 1974-10-31 | 1976-05-08 | Otsuka Pharma Co Ltd | Karubosuchirirujudotaino seizoho |
| JPS5152179A (ja) * | 1974-10-31 | 1976-05-08 | Otsuka Pharma Co Ltd | Karubosuchirirujudotaino seizoho |
| JPS5152178A (ja) * | 1974-10-31 | 1976-05-08 | Otsuka Pharma Co Ltd | Karubosuchirirujudotaino seizoho |
| FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
| US4081447A (en) * | 1975-04-09 | 1978-03-28 | Abbott Laboratories | 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof |
| CH619453A5 (da) * | 1976-03-17 | 1980-09-30 | Otsuka Pharma Co Ltd | |
| GB1574665A (en) * | 1976-05-08 | 1980-09-10 | Otsuka Pharma Co Ltd | 3,4-dihydrocarbostyril derivatives and process for preparing the same |
| US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| EP0005828B1 (de) * | 1978-06-06 | 1981-03-11 | Hoechst Aktiengesellschaft | Neue substituierte Phenylpiperazinderivate, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung |
| DE2827566A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Mannheim Gmbh | 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung |
| AU518814B2 (en) * | 1979-01-30 | 1981-10-22 | Otsuka Pharamaceutical Co. | Glaucoma treatment |
| DE3034237A1 (de) * | 1979-09-18 | 1981-04-16 | Otsuka Pharmaceutical Co. Ltd., Tokyo | Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel |
| JPS56122356A (en) * | 1980-02-29 | 1981-09-25 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
| JPS58103343A (ja) * | 1981-12-15 | 1983-06-20 | Ota Seiyaku Kk | プロパノ−ルアミン化合物の製造法 |
| JPS597186A (ja) * | 1982-07-02 | 1984-01-14 | Ota Seiyaku Kk | １，３，２−ジオキサチオラン２−オキシド誘導体 |
| JPS63193086U (da) * | 1987-05-30 | 1988-12-13 | ||
| DE3808136A1 (de) * | 1988-03-11 | 1989-09-21 | Thomae Gmbh Dr K | Arzneimittel, enthaltend chinolin-2,5-dione, neue chinolin-2,5-dione und verfahren zu ihrer herstellung |
| US5266577A (en) * | 1988-08-10 | 1993-11-30 | Otsuka Pharmaceutical Company Ltd. | Method of treating congestive heart failure using carbostyril derivatives |
| EP0355583B1 (en) * | 1988-08-10 | 1995-01-25 | Otsuka Pharmaceutical Co., Ltd. | Cardiotonics |
| CA2093633A1 (en) * | 1991-08-23 | 1993-02-24 | Seiji Sato | Carbostyril derivative and platelets aggregation inhibitory agent |
| ES2048108B1 (es) * | 1992-07-17 | 1994-10-01 | Lusochimica Spa | Procedimiento para la preparacion de 5-(3-terc-butilamino-2-hidroxipropoxi)-3,4-dihidrocarboestirilo. |
| IT1264816B1 (it) * | 1993-07-28 | 1996-10-10 | Pergam Srl | Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile |
| CZ300351B6 (cs) * | 2005-05-26 | 2009-04-29 | Zentiva, A. S. | Zpusob prípravy 7-hydroxy-3,4-dihydrokarbostyrilu |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
| CH523899A (de) * | 1968-07-05 | 1972-06-15 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von Derivaten des 2-Oxo-1,2-dihydro-chinolins |
-
1972
- 1972-04-13 JP JP47037181A patent/JPS517672B2/ja not_active Expired
- 1972-04-13 JP JP47037182A patent/JPS48103590A/ja active Pending
- 1972-12-02 JP JP47120953A patent/JPS5229745B2/ja not_active Expired
- 1972-12-14 JP JP47125858A patent/JPS5239036B2/ja not_active Expired
- 1972-12-21 JP JP47128972A patent/JPS5241269B2/ja not_active Expired
-
1973
- 1973-01-03 DK DK2773AA patent/DK141603B/da active Protection Beyond IP Right Term
- 1973-01-10 NO NO73105A patent/NO140589C/no unknown
- 1973-01-10 FR FR7300739A patent/FR2179715B1/fr not_active Expired
- 1973-01-11 CA CA161,000A patent/CA1025447A/en not_active Expired
- 1973-01-16 DE DE2302027A patent/DE2302027C2/de not_active Expired
- 1973-01-22 GB GB3417075A patent/GB1424572A/en not_active Expired
- 1973-01-22 GB GB325173A patent/GB1424571A/en not_active Expired
- 1973-01-29 BE BE794669D patent/BE794669A/xx active Protection Beyond IP Right Term
- 1973-01-31 FI FI279/73A patent/FI53703C/fi active
- 1973-02-02 DD DD178082*A patent/DD112446A5/xx unknown
- 1973-02-02 DD DD168643A patent/DD108293A5/xx unknown
- 1973-02-09 SE SE7301863A patent/SE380018B/xx unknown
- 1973-02-12 AR AR246548A patent/AR209575A1/es active
- 1973-02-20 NL NL7302353.A patent/NL158176B/xx not_active IP Right Cessation
- 1973-03-19 CH CH393973A patent/CH575929A5/xx active Protection Beyond IP Right Term
- 1973-04-11 AU AU54386/73A patent/AU475964B2/en not_active Expired
-
1979
- 1979-10-19 YU YU2549/79A patent/YU41187B/xx unknown
-
1981
- 1981-05-14 HK HK194/81A patent/HK19481A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2302027C2 (de) | 1983-03-17 |
| JPS5241269B2 (da) | 1977-10-17 |
| JPS5229745B2 (da) | 1977-08-03 |
| CH575929A5 (da) | 1976-05-31 |
| DD112446A5 (da) | 1975-04-12 |
| SE380018B (da) | 1975-10-27 |
| JPS5239036B2 (da) | 1977-10-03 |
| NO140589B (no) | 1979-06-25 |
| AU5438673A (en) | 1974-10-17 |
| NL158176B (nl) | 1978-10-16 |
| JPS48103590A (da) | 1973-12-25 |
| FI53703B (da) | 1978-03-31 |
| BE794669A (fr) | 1973-05-16 |
| NL7302353A (da) | 1973-10-16 |
| AU475964B2 (en) | 1976-09-09 |
| GB1424572A (en) | 1976-02-11 |
| YU254979A (en) | 1982-10-31 |
| FR2179715B1 (da) | 1976-12-03 |
| JPS517672B2 (da) | 1976-03-10 |
| GB1424571A (en) | 1976-02-11 |
| JPS4981373A (da) | 1974-08-06 |
| DK141603C (da) | 1980-10-06 |
| HK19481A (en) | 1981-05-22 |
| FR2179715A1 (da) | 1973-11-23 |
| DK141603B (da) | 1980-05-05 |
| NO140589C (no) | 1979-10-03 |
| DD108293A5 (da) | 1974-09-12 |
| YU41187B (en) | 1986-12-31 |
| JPS4982673A (da) | 1974-08-08 |
| JPS48103589A (da) | 1973-12-25 |
| JPS4976878A (da) | 1974-07-24 |
| CA1025447A (en) | 1978-01-31 |
| DE2302027A1 (de) | 1973-12-06 |
| FI53703C (fi) | 1978-07-10 |
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