AR080098A2 - CRYSTALLINE POLYMORPH COMPOUND OF THE ACID COMPOUND 6- (4-CHLOROPHENYL) -2,2-DIMETHYL-7-PHENYL-2,3 DIHYDRO-1H-PIRROLIZIN-5-ILACETICO, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE THIS LAST AND PROCESS TO PREPARE SUCH CRYSTAL POLYMORPH - Google Patents

CRYSTALLINE POLYMORPH COMPOUND OF THE ACID COMPOUND 6- (4-CHLOROPHENYL) -2,2-DIMETHYL-7-PHENYL-2,3 DIHYDRO-1H-PIRROLIZIN-5-ILACETICO, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE THIS LAST AND PROCESS TO PREPARE SUCH CRYSTAL POLYMORPH

Info

Publication number
AR080098A2
AR080098A2 ARP110100332A AR080098A2 AR 080098 A2 AR080098 A2 AR 080098A2 AR P110100332 A ARP110100332 A AR P110100332A AR 080098 A2 AR080098 A2 AR 080098A2
Authority
AR
Argentina
Prior art keywords
prepare
compound
pharmaceutical composition
polymorph
pirrolizin
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Thomas Kammermeier
Stefan Laufer
Philipp Merckle
Hans-Gunter Striegel
Original Assignee
Merckle Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merckle Gmbh filed Critical Merckle Gmbh
Priority to ARP110100332 priority Critical patent/AR080098A2/en
Publication of AR080098A2 publication Critical patent/AR080098A2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compuesto polimorfo cristalino, de la formula (1) que tiene una unica línea endotérmica en el diagrama de DSC, que está dentro del rango que oscila entre 155 y 170°C. Composicion farmacéutica que lo comprende, su uso para preparar esta ultima y proceso para preparar dicho polimorfo cristalino. Uso del compuesto para preparar una composicion farmacéutica para el tratamiento de trastornos de tipo reumático. Reivindicacion 2: Compuesto de acuerdo con la reivindicacion 1, caracterizado porque tiene los siguientes picos significativos en el espectro IR (numero de onda, cm-1): 1706; 1601; 1536; 1487; 1463; 1450; 1441; 1413; 1395; 1383; 1369; 1293; 1219; 1177; 1099; 1013; 836; 765; 698.Crystalline polymorphic compound, of the formula (1) having a unique endothermic line in the DSC diagram, which is within the range of 155 to 170 ° C. Pharmaceutical composition comprising it, its use to prepare the latter and process to prepare said crystalline polymorph. Use of the compound to prepare a pharmaceutical composition for the treatment of rheumatic disorders. Claim 2: Compound according to claim 1, characterized in that it has the following significant peaks in the IR spectrum (wave number, cm-1): 1706; 1601; 1536; 1487; 1463; 1450; 1441; 1413; 1395; 1383; 1369; 1293; 1219; 1177; 1099; 1013; 836; 765; 698.

ARP110100332 2011-02-01 2011-02-01 CRYSTALLINE POLYMORPH COMPOUND OF THE ACID COMPOUND 6- (4-CHLOROPHENYL) -2,2-DIMETHYL-7-PHENYL-2,3 DIHYDRO-1H-PIRROLIZIN-5-ILACETICO, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE THIS LAST AND PROCESS TO PREPARE SUCH CRYSTAL POLYMORPH AR080098A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP110100332 AR080098A2 (en) 2011-02-01 2011-02-01 CRYSTALLINE POLYMORPH COMPOUND OF THE ACID COMPOUND 6- (4-CHLOROPHENYL) -2,2-DIMETHYL-7-PHENYL-2,3 DIHYDRO-1H-PIRROLIZIN-5-ILACETICO, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE THIS LAST AND PROCESS TO PREPARE SUCH CRYSTAL POLYMORPH

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP110100332 AR080098A2 (en) 2011-02-01 2011-02-01 CRYSTALLINE POLYMORPH COMPOUND OF THE ACID COMPOUND 6- (4-CHLOROPHENYL) -2,2-DIMETHYL-7-PHENYL-2,3 DIHYDRO-1H-PIRROLIZIN-5-ILACETICO, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE THIS LAST AND PROCESS TO PREPARE SUCH CRYSTAL POLYMORPH

Publications (1)

Publication Number Publication Date
AR080098A2 true AR080098A2 (en) 2012-03-14

Family

ID=45830848

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110100332 AR080098A2 (en) 2011-02-01 2011-02-01 CRYSTALLINE POLYMORPH COMPOUND OF THE ACID COMPOUND 6- (4-CHLOROPHENYL) -2,2-DIMETHYL-7-PHENYL-2,3 DIHYDRO-1H-PIRROLIZIN-5-ILACETICO, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE THIS LAST AND PROCESS TO PREPARE SUCH CRYSTAL POLYMORPH

Country Status (1)

Country Link
AR (1) AR080098A2 (en)

Similar Documents

Publication Publication Date Title
UY33547A (en) CHEMICAL COMPOUNDS Bcl-2 and Bcl-XL
DOP2016000281A (en) IMIDAZO COMPOUNDS [4,5-C] QUINOLIN-2-ONA AND ITS USE TO TREAT CANCER
CO2018003969A2 (en) Imidazo [4,5-c] quinolin-2-one compounds
CL2014001174A1 (en) Compounds derived from [1,2,3] triazolo [4,5-d] pyrimidine and their salts, as cannabinoid receptor agonists 2; its process of obtaining; pharmaceutical composition that contains them; and its use for the treatment or prophylaxis of pain, atherosclerosis, inflammation, glaucoma, transient ischemic attack, among other diseases.
CL2009001066A1 (en) Compounds derived from substituted carboxylic acid cyclopentane; lpa edg2 receptor inhibitors; pharmaceutical composition; preparation procedure; and use in the treatment of cardiovascular, inflammatory, metabolic, kidney, lung, oncological, immunological and allergy diseases, among others.
PE20211782A1 (en) COMPOSITIONS OF 5-CHLORO-2-DIFLUOROMETOXIFENIL PYRAZOLOPYRIMIDINE, COMPOSITIONS AND METHODS OF USE OF THE SAME
CR10288A (en) PIRAZOLES AS INHIBITORS OF THE 11-BETA-HSD1
DOP2018000115A (en) IMIDAZO COMPOUNDS [4,5-C] QUINOLIN-2-ONA AND ITS USE IN CANCER TREATMENT
BR112014030795A2 (en) compound, pharmaceutical composition, use of a compound and process for preparing a compound
CU24603B1 (en) SUBSTITUTED DIAZABICYCLIC IMIDAZOPYRIMIDINES USEFUL IN THE TREATMENT OF RESPIRATORY DISORDERS
CO7131357A2 (en) N-aryltriazole compounds as lpar antagonists
CU20130036A7 (en) TRIAZINA-OXIDAZOLES
CL2012003722A1 (en) Compounds derived from naf-2-ylacetic acid; pharmaceutical composition; and use for the treatment of AIDS.
AR094964A1 (en) USE OF PIRAZOLOPIRIMIDINE DERIVATIVES FOR THE TREATMENT OF PHOSFOINOSITIDE-RELATED 3-CINASE D (PI3Kd)
CL2012003546A1 (en) Specific compounds 2- (3- (4-cyanonaphthalen-1-yl) pyridin-4-ylthio) -2-methylprpanoic acid, in use fromula markush; pharmaceutical composition and combination that includes it; and use of the compound and the pharmaceutical combination in the preparation of medicaments for treating diseases caused by high levels of uric acid.
DOP2012000263A (en) CHEMICAL COMPOUNDS
UY32483A (en) NEW BENCIMIDAZOL COMPOUNDS FOR THE TREATMENT OF RESPIRATORY SINCICIAL VIRUS
CR11582A (en) HETEROCICLICAL COMPOUNDS AND THEIR USES
CO6771439A2 (en) Benzodioxane inhibitors of leukotriene production
ECSP13012519A (en) BENZAMIDA SUBSTITUTED COMPOUNDS
UY31885A (en) DERIVED FROM THE 1, 3, 5-TRIAZINA-2, 4-DIAMINAS-6-SUBSTITUTED-N-SUBSTITUTED AND PHARMACEUTICALLY ACCEPTABLE SALTS OF THE SAME, COMPOSITIONS AND APPLICATIONS.
EA201300862A1 (en) INHIBITION OF IL17 AND IFN-GAMMA FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATION
BR112014012358A2 (en) 2-oxo-1,3-dioxolane-4-carboxamides, their preparation and use
UY32622A (en) NEW COMPOUNDS FOR THE TREATMENT OF PATHOLOGIES RELATED TO AB (BETA)
AR102981A1 (en) INHIBITORS OF CELL NECROSIS AND METHODS OF PREPARATION OF THE SAME

Legal Events

Date Code Title Description
FC Refusal