AR077666A2 - VACCINE COMPOSITIONS AGAINST THE VIRUS OF NEWCASTLE DISEASE AND METHODS TO DEVELOP SUCH COMPOSITIONS - Google Patents

VACCINE COMPOSITIONS AGAINST THE VIRUS OF NEWCASTLE DISEASE AND METHODS TO DEVELOP SUCH COMPOSITIONS

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Publication number
AR077666A2
AR077666A2 ARP100102814A AR077666A2 AR 077666 A2 AR077666 A2 AR 077666A2 AR P100102814 A ARP100102814 A AR P100102814A AR 077666 A2 AR077666 A2 AR 077666A2
Authority
AR
Argentina
Prior art keywords
immunogenic
protein
compositions
newcastle disease
disease virus
Prior art date
Application number
Other languages
English (en)
Inventor
Osvaldo Zsbal
Alejandro Tozzini
Oscar Taboga
Analia Berinstein
Esteban Hopp
Flavia Zanetti
Grand Daniela Conte
Elisa Carrillo
Sebastian Asurmendi
Rovere Cecilia Vazquez
Original Assignee
Inst Nac De Tecnologia Agropecuaria
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nac De Tecnologia Agropecuaria filed Critical Inst Nac De Tecnologia Agropecuaria
Priority to ARP100102814 priority Critical patent/AR077666A2/es
Publication of AR077666A2 publication Critical patent/AR077666A2/es

Links

Abstract

Composiciones de vacunas contra el virus de la enfermedad de Newcastle y métodos para elaborar dichas composiciones, que comprenden cassettes de ADN para la expresion de al menos una proteína inmunogénica viral, donde dicha proteína inmunogénica se expresa en plantas y comprende una secuencia de ADN que codifica al menos una proteína inmunogénica del virus de la enfermedad de Newcastle operablemente unida a; secuencias que controlan la transcripcion y traduccion de dicha proteína inmunogénica en las plantas, en donde la proteína inmunogénica expresada es util para inmunizar animales contra el virus de la enfermedad de Newcastle. Dicha proteína inmunogénica puede ser la proteína hemoaglutinina-neuraminidasa (HN) o la proteína de fusion (F). Los vectores comprenden uno o más cassettes de expresion de dichas proteínas inmunogénicas y los mismos son utilizados para transformar establemente células vegetales para la obtencion de plantas transgénicas que expresan dichas proteínas virales inmunogénicas. Las plantas transgénicas o partes de las mismas se pueden utilizar como composiciones de vacunas comestibles o para la elaboracion de composiciones de vacunas inyectables para inmunizar animales contra el virus de la enfermedad de Newcastle.Compositions of vaccines against the Newcastle disease virus and methods for making said compositions, comprising DNA cassettes for the expression of at least one viral immunogenic protein, wherein said immunogenic protein is expressed in plants and comprises a DNA sequence encoding at least one immunogenic Newcastle disease virus protein operably linked to; sequences that control the transcription and translation of said immunogenic protein in plants, wherein the expressed immunogenic protein is useful for immunizing animals against the Newcastle disease virus. Said immunogenic protein may be the hemoagglutinin-neuraminidase protein (HN) or the fusion protein (F). The vectors comprise one or more expression cassettes of said immunogenic proteins and they are used to stably transform plant cells to obtain transgenic plants that express said immunogenic viral proteins. Transgenic plants or parts thereof can be used as edible vaccine compositions or for the preparation of injectable vaccine compositions to immunize animals against the Newcastle disease virus.
ARP100102814 2010-08-02 2010-08-02 VACCINE COMPOSITIONS AGAINST THE VIRUS OF NEWCASTLE DISEASE AND METHODS TO DEVELOP SUCH COMPOSITIONS AR077666A2 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP100102814 AR077666A2 (es) 2010-08-02 2010-08-02 VACCINE COMPOSITIONS AGAINST THE VIRUS OF NEWCASTLE DISEASE AND METHODS TO DEVELOP SUCH COMPOSITIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP100102814 AR077666A2 (es) 2010-08-02 2010-08-02 VACCINE COMPOSITIONS AGAINST THE VIRUS OF NEWCASTLE DISEASE AND METHODS TO DEVELOP SUCH COMPOSITIONS

Publications (1)

Publication Number Publication Date
AR077666A2 true AR077666A2 (es) 2011-09-14

Family

ID=44764643

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100102814 AR077666A2 (es) 2010-08-02 2010-08-02 VACCINE COMPOSITIONS AGAINST THE VIRUS OF NEWCASTLE DISEASE AND METHODS TO DEVELOP SUCH COMPOSITIONS

Country Status (1)

Country Link
AR (1) AR077666A2 (es)

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