AR076856A1 - LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATION - Google Patents
LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATIONInfo
- Publication number
- AR076856A1 AR076856A1 ARP100101577A ARP100101577A AR076856A1 AR 076856 A1 AR076856 A1 AR 076856A1 AR P100101577 A ARP100101577 A AR P100101577A AR P100101577 A ARP100101577 A AR P100101577A AR 076856 A1 AR076856 A1 AR 076856A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- lenalidomide
- polymorph
- crystalline
- theta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente solicitud se relaciona con una forma cristalina de la lenalidomida, procesos para su preparacion, y el uso de la forma polimorfica en la preparacion de composiciones farmacéuticas. Reivindicacion 1: Lenalidomida cristalina con un patron de difraccion de rayos-x en polvo que comprende uno o más picos localizados en las posiciones 8,29; 25,9 y 27,5 0,2 grados 2-theta.The present application relates to a crystalline form of lenalidomide, processes for its preparation, and the use of the polymorphic form in the preparation of pharmaceutical compositions. Claim 1: Crystalline Lenalidomide with a powder x-ray diffraction pattern comprising one or more peaks located at positions 8.29; 25.9 and 27.5 0.2 degrees 2-theta.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1079CH2009 | 2009-05-08 | ||
US22652409P | 2009-07-17 | 2009-07-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR076856A1 true AR076856A1 (en) | 2011-07-13 |
Family
ID=43050836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100101577A AR076856A1 (en) | 2009-05-08 | 2010-05-07 | LENALIDOMIDE POLYMORPH AND PROCESS FOR PREPARATION |
Country Status (2)
Country | Link |
---|---|
AR (1) | AR076856A1 (en) |
WO (1) | WO2010129636A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA83504C2 (en) | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
TWI475014B (en) * | 2009-09-17 | 2015-03-01 | Scinopharm Taiwan Ltd | Solid forms of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2, 6-dione and methods of making the same |
WO2011061611A1 (en) * | 2009-11-19 | 2011-05-26 | Ranbaxy Laboratories Limited | Process for the preparation of form b of lenalidomide |
WO2012127493A1 (en) | 2011-03-23 | 2012-09-27 | Hetero Research Foundation | Polymorphs of lenalidomide |
WO2016024286A2 (en) * | 2014-08-11 | 2016-02-18 | Avra Laboratories Pvt. Ltd. | An improved process for synthesis of lenalidomide |
ES2811110T3 (en) * | 2015-08-27 | 2021-03-10 | Grindeks Jsc | Pharmaceutical composition capable of incorporating Lenalidomide in various crystalline modifications |
TWI664172B (en) * | 2016-08-25 | 2019-07-01 | 大陸商浙江海正藥業股份有限公司 | Crystal form of lenalidomide, preparation method and application thereof |
CN112999224B (en) * | 2021-03-03 | 2022-09-16 | 天津大学 | Ibuprofen-loaded lenalidomide composite particle and preparation method thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5635517B1 (en) * | 1996-07-24 | 1999-06-29 | Celgene Corp | Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines |
UA83504C2 (en) * | 2003-09-04 | 2008-07-25 | Селджин Корпорейшн | Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione |
-
2010
- 2010-05-05 WO PCT/US2010/033661 patent/WO2010129636A2/en active Application Filing
- 2010-05-07 AR ARP100101577A patent/AR076856A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2010129636A2 (en) | 2010-11-11 |
WO2010129636A3 (en) | 2011-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |