AR047350A1 - Genes que codifican proteinas con actividad plaguicida - Google Patents
Genes que codifican proteinas con actividad plaguicidaInfo
- Publication number
- AR047350A1 AR047350A1 ARP040104900A ARP040104900A AR047350A1 AR 047350 A1 AR047350 A1 AR 047350A1 AR P040104900 A ARP040104900 A AR P040104900A AR P040104900 A ARP040104900 A AR P040104900A AR 047350 A1 AR047350 A1 AR 047350A1
- Authority
- AR
- Argentina
- Prior art keywords
- plant
- compositions
- methods
- proteolytic
- pesticidal polypeptides
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108091005804 Peptidases Proteins 0.000 abstract 4
- 239000004365 Protease Substances 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 241000607479 Yersinia pestis Species 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 230000000361 pesticidal effect Effects 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000035195 Peptidases Human genes 0.000 abstract 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 230000002797 proteolythic effect Effects 0.000 abstract 2
- 241000238631 Hexapoda Species 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 230000017854 proteolysis Effects 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Insects & Arthropods (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Composiciones y métodos para proteger una planta contra plagas de insectos, se proveen ácidos nucleicos mutagenizados que han sido modificados para codificar polipéptidos plaguicidas que tienen más resistencia a la degradacion proteolítica por una proteasa vegetal. En particular, se proporcionan secuencias de ácidos nucleicos que codifican polipéptidos plaguicidas, modificadas para que comprendan un sitio de proteccion proteolítica que confiere resistencia a la degradacion o la inactividad proteolítica por una proteasa vegetal. Se proporcionan composiciones y formulaciones de polipéptidos plaguicidas, cassettes de expresion y plantas, células vegetales y semillas transformadoras. Estas composiciones pueden usarse en métodos para controlar plagas, especialmente plagas que afectan plantas. También se proporcionan nuevas proteasas vegetales, secuencias que codifican estas proteasas y métodos para usarlas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/746,914 US7462760B2 (en) | 2002-06-26 | 2003-12-24 | Genes encoding plant protease-resistant pesticidal proteins and method of their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR047350A1 true AR047350A1 (es) | 2006-01-18 |
Family
ID=34749249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040104900A AR047350A1 (es) | 2003-12-24 | 2004-12-27 | Genes que codifican proteinas con actividad plaguicida |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7462760B2 (es) |
| EP (1) | EP1699816A2 (es) |
| AR (1) | AR047350A1 (es) |
| BR (1) | BRPI0418163A (es) |
| CA (1) | CA2551102C (es) |
| WO (1) | WO2005066349A2 (es) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7605304B2 (en) * | 2000-10-24 | 2009-10-20 | E.I. Du Pont De Nemours And Company | Genes encoding novel bacillus thuringiensis proteins with pesticidal activity against coleopterans |
| EP1531664A4 (en) * | 2002-06-26 | 2005-11-16 | Du Pont | GENES ENCODING PROTEINS WITH PESTICIDAL ACTIVITY |
| EP1893638B1 (en) | 2005-06-08 | 2011-08-10 | Pioneer-Hi-Bred International, Inc. | Insect-specific protease recognition sequences |
| US7792856B2 (en) * | 2007-06-29 | 2010-09-07 | International Business Machines Corporation | Entity-based business intelligence |
| UA108348C2 (uk) * | 2009-01-23 | 2015-04-27 | Піонер Хай-Бред Інтернешнл, Інк. | Ген bacillus thuringiensis з активністю проти lepidoptera |
| EP2458009B1 (en) * | 2009-07-24 | 2024-09-04 | EMBRAPA - Empresa Brasileira De Pesquisa Agropecuária | Isolated nucleic acid molecule, genetic construct, vector, transgenic cell, method for producing a transgenic cell and plant, isolated and purified polypeptide, biodegradable pesticide composition, pest control method, method for producing transgenic strains resistant to insect pests |
| WO2011009182A2 (pt) * | 2009-07-24 | 2011-01-27 | Embrapa - Empresa Brasileira De Pesquisa Agropecuária | Molécula de ácido nucléico isolada, construção gênica, vetor, célula transgênica, método para obtenção de uma célula e de uma planta transgênica, polipeptídeo isolado e purificado, composição pesticida biodegradável, método para o controle de uma praga, método de obtenção de linhagens transgênicas resistentes a um inseto praga |
| BR112013015515A2 (pt) | 2010-12-28 | 2018-04-24 | Pioneer Hi Bred Int | molécula de ácido nucleico isolada, construto de dna, célula hospedeira, planta transgênica, semente transformada da planta, polipeptídeo isolado com atividade pesticida, composição, método para controlar uma população de praga de lepidóptero, método para matar uma praga de lepidóptero, método para produzir um polipeptídeo com atividade pesticida, planta que tem incorporado de maneira estável em seu genoma um construto de dna, método para proteger uma planta contra uma praga |
| US8878007B2 (en) | 2011-03-10 | 2014-11-04 | Pioneer Hi Bred International Inc | Bacillus thuringiensis gene with lepidopteran activity |
| BR112015008504A2 (pt) | 2012-10-15 | 2017-08-22 | Pioneer Hi Bred Int | Método para aumentar a atividade pesticida, polipeptídeo, molécula de ácido nucleico, cassete de expressão, vetor, método de obtenção de uma planta, método de obtenção de uma célula de planta, composição pesticida, método para proteção de uma planta, método para proteger uma planta, método para aumentar a resistência de uma planta |
| US10968446B2 (en) | 2012-11-01 | 2021-04-06 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
| WO2014153254A2 (en) | 2013-03-14 | 2014-09-25 | Pioneer Hi-Bred International Inc. | Compositions and methods to control insect pests |
| CN105473605A (zh) | 2013-03-15 | 2016-04-06 | 先锋国际良种公司 | Phi-4多肽及其使用方法 |
| CA3184796A1 (en) | 2013-08-08 | 2015-02-12 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides having broad spectrum activity and uses thereof |
| CN106232820A (zh) | 2013-08-16 | 2016-12-14 | 先锋国际良种公司 | 杀昆虫蛋白及其使用方法 |
| ES2937045T3 (es) | 2013-09-13 | 2023-03-23 | Pioneer Hi Bred Int | Proteínas insecticidas y métodos para su uso |
| RU2021113662A (ru) | 2014-02-07 | 2021-05-31 | Пайонир Хай-Бред Интернэшнл, Инк. | Инсектицидные белки и способы их применения |
| US10480007B2 (en) | 2014-02-07 | 2019-11-19 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants |
| WO2016000237A1 (en) | 2014-07-03 | 2016-01-07 | Pioneer Overseas Corporation | Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes |
| US10028510B2 (en) | 2014-08-28 | 2018-07-24 | Dow Agrosciences Llc | DIG-17 insecticidal cry toxins |
| WO2016032836A1 (en) * | 2014-08-28 | 2016-03-03 | Dow Agrosciences Llc | Dig-14 insecticidal cry toxins |
| WO2016044092A1 (en) | 2014-09-17 | 2016-03-24 | Pioneer Hi Bred International Inc | Compositions and methods to control insect pests |
| BR112017007929A2 (pt) * | 2014-10-15 | 2018-01-23 | Du Pont | polipeptídeo, molécula de ácido nucleico, construto de dna, célula hospedeira, planta transgênica, semente, composição, método para controlar uma população de praga, método para exterminar uma praga, método para produzir um polipeptídeo, planta ou célula vegetal, método para proteger uma planta |
| BR112017007927A2 (pt) | 2014-10-16 | 2018-03-20 | Pioneer Hi Bred Int | polipeptídeos inseticidas com espectro de atividade melhorado e seus usos |
| UA126192C2 (uk) | 2014-10-16 | 2022-08-31 | Піонір Хай-Бред Інтернешнл, Інк. | Інсектицидний білок та спосіб його застосування |
| CA2963550A1 (en) | 2014-10-16 | 2016-04-21 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides having broad spectrum activity and uses thereof |
| MX2017011525A (es) | 2015-03-11 | 2018-01-30 | Pioneer Hi Bred Int | Combinaciones insecticidas de pip-72 y metodos de uso. |
| CA2985198A1 (en) | 2015-05-19 | 2016-11-24 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CA2986265A1 (en) | 2015-06-16 | 2016-12-22 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| EP3322679A4 (en) | 2015-07-13 | 2019-07-10 | Pivot Bio, Inc. | METHODS AND COMPOSITIONS FOR IMPROVING THE CHARACTERISTICS OF A PLANT |
| CA2994676A1 (en) | 2015-08-06 | 2017-02-09 | Pioneer Hi-Bred International, Inc. | Plant derived insecticidal proteins and methods for their use |
| DK3341483T3 (da) | 2015-08-28 | 2020-03-16 | Pioneer Hi Bred Int | Ochrobactrum-medieret transformation af planter |
| US11479516B2 (en) | 2015-10-05 | 2022-10-25 | Massachusetts Institute Of Technology | Nitrogen fixation using refactored NIF clusters |
| CA3002995A1 (en) | 2015-12-18 | 2017-06-22 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CN117003840A (zh) | 2016-04-14 | 2023-11-07 | 先锋国际良种公司 | 具有改善的活性谱的杀昆虫多肽及其用途 |
| CA3021391A1 (en) | 2016-04-19 | 2017-10-26 | Pioneer Hi-Bred International, Inc. | Insecticidal combinations of polypeptides having improved activity spectrum and uses thereof |
| EP3960863A1 (en) | 2016-05-04 | 2022-03-02 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| US20190185867A1 (en) | 2016-06-16 | 2019-06-20 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| EP3475430B1 (en) | 2016-06-24 | 2022-06-01 | Pioneer Hi-Bred International, Inc. | Plant regulatory elements and methods of use thereof |
| EP3954202A1 (en) | 2016-07-01 | 2022-02-16 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
| US20210292778A1 (en) | 2016-07-12 | 2021-09-23 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| CN116003539A (zh) | 2016-11-01 | 2023-04-25 | 先锋国际良种公司 | 杀昆虫蛋白及其使用方法 |
| CN116199752A (zh) * | 2016-12-12 | 2023-06-02 | 先正达参股股份有限公司 | 工程化的杀有害生物蛋白和控制植物有害生物的方法 |
| EP3555118B1 (en) | 2016-12-14 | 2021-08-18 | Pioneer Hi-Bred International Inc. | Insecticidal proteins and methods for their use |
| US11213028B2 (en) | 2016-12-22 | 2022-01-04 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| JP7234116B2 (ja) | 2017-01-12 | 2023-03-07 | ピボット バイオ， インコーポレイテッド | 植物形質を改善するための方法および組成物 |
| WO2018140214A1 (en) | 2017-01-24 | 2018-08-02 | Pioneer Hi-Bred International, Inc. | Nematicidal protein from pseudomonas |
| WO2018148001A1 (en) | 2017-02-08 | 2018-08-16 | Pioneer Hi-Bred International Inc | Insecticidal combinations of plant derived insecticidal proteins and methods for their use |
| CA3064884A1 (en) | 2017-05-26 | 2018-11-29 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides having improved activity spectrum and uses thereof |
| US20200165626A1 (en) | 2017-10-13 | 2020-05-28 | Pioneer Hi-Bred International, Inc. | Virus-induced gene silencing technology for insect control in maize |
| WO2019084059A2 (en) | 2017-10-25 | 2019-05-02 | Pivot Bio, Inc. | METHODS AND COMPOSITIONS FOR ENHANCING GENETICALLY MODIFIED MICROBES THAT FIX NITROGEN |
| WO2019125651A1 (en) | 2017-12-19 | 2019-06-27 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides and uses thereof |
| WO2019165245A1 (en) | 2018-02-22 | 2019-08-29 | Zymergen Inc. | Method for creating a genomic library enriched for bacillus and identification of novel cry toxins |
| CN111770995A (zh) | 2018-03-02 | 2020-10-13 | 齐默尔根公司 | 杀昆虫蛋白发现平台和自其发现的杀昆虫蛋白 |
| US20210002657A1 (en) | 2018-03-02 | 2021-01-07 | Pioneer Hi-Bred International, Inc. | Plant health assay |
| WO2019178042A1 (en) | 2018-03-14 | 2019-09-19 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
| EP3764796A4 (en) | 2018-03-14 | 2021-12-22 | Pioneer Hi-Bred International, Inc. | INSECTICIDAL PROTEINS FROM PLANTS AND METHOD OF USING THEM |
| CA3096516A1 (en) | 2018-05-22 | 2019-11-28 | Pioneer Hi-Bred International, Inc. | Plant regulatory elements and methods of use thereof |
| BR112020026771A2 (pt) | 2018-06-27 | 2021-03-30 | Pivot Bio, Inc. | Composições agrícolas que compreendem micróbios de fixação de nitrogênio remodelados |
| CA3106444A1 (en) | 2018-08-29 | 2020-03-05 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for conferring pesticidal activity to plants |
| WO2021076346A1 (en) | 2019-10-18 | 2021-04-22 | Pioneer Hi-Bred International, Inc. | Maize event dp-202216-6 and dp-023211-2 stack |
| WO2021221690A1 (en) | 2020-05-01 | 2021-11-04 | Pivot Bio, Inc. | Modified bacterial strains for improved fixation of nitrogen |
| TW202142114A (zh) | 2020-02-04 | 2021-11-16 | 美商陶氏農業科學公司 | 具有殺有害生物效用之組成物及與其相關之方法 |
| CA3172322A1 (en) | 2020-05-01 | 2021-11-04 | Karsten TEMME | Modified bacterial strains for improved fixation of nitrogen |
| US20230235352A1 (en) | 2020-07-14 | 2023-07-27 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CN116096903A (zh) | 2020-08-10 | 2023-05-09 | 先锋国际良种公司 | 植物调节元件及其使用方法 |
| MX2024000026A (es) | 2021-07-02 | 2024-02-20 | Pivot Bio Inc | Cepas bacterianas dise?adas por ingenieria genetica para fijacion de nitrogeno mejorada. |
| TW202345696A (zh) | 2022-05-18 | 2023-12-01 | 美商科迪華農業科技有限責任公司 | 具有殺有害生物效用之組成物及與其相關的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5185148A (en) | 1991-12-16 | 1993-02-09 | Mycogen Corporation | Process for controlling scarab pests with Bacillus thuringiensis isolates |
| US5554534A (en) * | 1991-12-16 | 1996-09-10 | Mycogen Corporation | Bacillus thuringiensis toxins active against scarab pests |
| US5849870A (en) | 1993-03-25 | 1998-12-15 | Novartis Finance Corporation | Pesticidal proteins and strains |
| US5659123A (en) | 1994-08-26 | 1997-08-19 | Plant Genetic Systems, N.V. | Diabrotica toxins |
| US5942664A (en) | 1996-11-27 | 1999-08-24 | Ecogen, Inc. | Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants |
| US6077824A (en) | 1997-12-18 | 2000-06-20 | Ecogen, Inc. | Methods for improving the activity of δ-endotoxins against insect pests |
| EP1801220B1 (en) | 1997-12-18 | 2012-02-08 | Monsanto Technology, LLC | Insect-resistant transgenic plants and methods for improving delta-endotoxin activity against insects |
| US6023013A (en) | 1997-12-18 | 2000-02-08 | Monsanto Company | Insect-resistant transgenic plants |
| US6063597A (en) | 1997-12-18 | 2000-05-16 | Monsanto Company | Polypeptide compositions toxic to coleopteran insects |
| US6060594A (en) | 1997-12-18 | 2000-05-09 | Ecogen, Inc. | Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins |
| US6501009B1 (en) | 1999-08-19 | 2002-12-31 | Monsanto Technology Llc | Expression of Cry3B insecticidal protein in plants |
| US7605304B2 (en) | 2000-10-24 | 2009-10-20 | E.I. Du Pont De Nemours And Company | Genes encoding novel bacillus thuringiensis proteins with pesticidal activity against coleopterans |
| US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
| EP1531664A4 (en) | 2002-06-26 | 2005-11-16 | Du Pont | GENES ENCODING PROTEINS WITH PESTICIDAL ACTIVITY |
-
2003
- 2003-12-24 US US10/746,914 patent/US7462760B2/en not_active Expired - Fee Related
-
2004
- 2004-12-09 EP EP04813794A patent/EP1699816A2/en not_active Withdrawn
- 2004-12-09 CA CA2551102A patent/CA2551102C/en not_active Expired - Fee Related
- 2004-12-09 BR BRPI0418163-8A patent/BRPI0418163A/pt not_active Application Discontinuation
- 2004-12-09 WO PCT/US2004/041530 patent/WO2005066349A2/en active Application Filing
- 2004-12-27 AR ARP040104900A patent/AR047350A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005066349A2 (en) | 2005-07-21 |
| WO2005066349A3 (en) | 2005-10-27 |
| CA2551102A1 (en) | 2005-07-21 |
| BRPI0418163A (pt) | 2007-06-19 |
| CA2551102C (en) | 2012-08-07 |
| EP1699816A2 (en) | 2006-09-13 |
| US20040210963A1 (en) | 2004-10-21 |
| US7462760B2 (en) | 2008-12-09 |
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