AR045466A1 - Productos de tabaco con exposicion reducida - Google Patents
Productos de tabaco con exposicion reducidaInfo
- Publication number
- AR045466A1 AR045466A1 ARP040102977A ARP040102977A AR045466A1 AR 045466 A1 AR045466 A1 AR 045466A1 AR P040102977 A ARP040102977 A AR P040102977A AR P040102977 A ARP040102977 A AR P040102977A AR 045466 A1 AR045466 A1 AR 045466A1
- Authority
- AR
- Argentina
- Prior art keywords
- nicotine
- plant
- tobacco
- production
- content
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/243—Nicotine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
Abstract
Se proveen metodologías, entre ellas, la utilización de tabacos genéticamente modificados (GM), para el desarrollo y producción de (PREP) productos potenciales de exposición reducida aceptables para el consumidor, que abarcan los siguientes: 1) producción de cigarrillos con baja relación de alquitrán a nicotina, lo que permite a los fumadores obtener cantidades satisfactorias de nicotina de manera más eficaz que con los cigarrillos convencionales, mientras que a la vez, se reducen las liberaciones de humo total, disminuyendo de ese modo la "compensación" del fumador que se presenta con cigarrillos de baja producción convencionales; 2) reducción de nitrosaminas específicas de tabaco nocivas en productos de tabaco, por medios genéticos, extracción de nicotina de tabaco y combinación de ésta con tabaco con menor contenido de nicotina genéticamente modificado; 3) producción de tabaco expandido mejorado, en donde se emplea tabaco con mayor contenido de nicotina genéticamente modificado; y 4) producción de tabaco reconstituido, que comprende cualquier combinación de los siguientes: tabaco con mayor contenido de nicotina genéticamente modificado, tabaco con menor contenido de nicotina genéticamente modificado, fracciones de hoja de tabaco y tabaco liofilizado recientemente cosechado. Reivindicación 1: Un cigarrillo que comprende: una planta o porción de planta transgénica de una especie del género Nicotina con mayor contenido de nicotina, en donde dicha planta o porción de planta expresa por lo menos un ácido nucleico heterólogo que regula en forma ascendente la producción de nicotina en dicha planta o porción de planta transgénica; y una relación de producción de alquitrán a nicotina de entre aproximadamente 3 y aproximadamente 8, medida por el método FTC o ISO. Reivindicación 20: Un método para la elaboración de un cigarrillo, que comprende: proveer una planta o porción de planta transgénica de una especie del género Nicotina con mayor contenido de alcaloide en comparación con una planta o porción de planta de control no transformada; cruzar dicha planta con una planta de la especie Nicotina tabacum a fin de obtener una planta de progenie, en donde dicha planta de progenie tiene un fenotipo de mayor contenido de nicotina; y producir un cigarrillo que comprende dicha planta de progenie y que tiene una relación de producción de alquitrán a nicotina de entre aproximadamente 3 y aproximadamente 8, medida por el método FTC o ISO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49629003P | 2003-08-19 | 2003-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR045466A1 true AR045466A1 (es) | 2005-10-26 |
Family
ID=34215981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040102977A AR045466A1 (es) | 2003-08-19 | 2004-08-19 | Productos de tabaco con exposicion reducida |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9814258B2 (es) |
| EP (1) | EP1675454A4 (es) |
| JP (1) | JP2007502621A (es) |
| KR (1) | KR20060128821A (es) |
| CN (1) | CN1838878A (es) |
| AP (1) | AP2265A (es) |
| AR (1) | AR045466A1 (es) |
| AU (1) | AU2004266694A1 (es) |
| BR (1) | BRPI0413733A (es) |
| CA (1) | CA2535763A1 (es) |
| EA (1) | EA200600449A1 (es) |
| MX (1) | MXPA06001591A (es) |
| OA (1) | OA13241A (es) |
| WO (1) | WO2005018307A1 (es) |
| ZA (1) | ZA200600749B (es) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7798153B2 (en) | 2004-08-23 | 2010-09-21 | Us Smokeless Tobacco Co. | Nicotiana Kawakamii smokeless tobacco |
| KR101563998B1 (ko) | 2005-02-28 | 2015-10-28 | 22엔디 센츄리 리미티드, 엘엘씨 | 식물의 니코틴 알칼로이드 수준의 감소 |
| AU2006247739A1 (en) | 2005-05-11 | 2006-11-23 | Vector Tobacco Inc. | Reduced risk tobacco products and methods of making same |
| CA2997344C (en) | 2006-06-19 | 2023-04-04 | 22Nd Century Limited, Llc | Nucleic acid encoding n-methylputrescine oxidase and uses thereof |
| US9551003B2 (en) * | 2006-09-13 | 2017-01-24 | 22Nd Century Limited, Llc | Increasing levels of nicotinic alkaloids in plants |
| ES2748823T3 (es) * | 2006-09-13 | 2020-03-18 | 22Nd Century Ltd Llc | Aumento de los niveles de alcaloides nicotínicos |
| US9102948B2 (en) | 2006-11-17 | 2015-08-11 | 22Nd Century Limited, Llc | Regulating alkaloids |
| CN110885834B (zh) * | 2007-05-25 | 2023-08-11 | 22世纪有限责任公司 | 编码调节生物碱合成之转录因子的核酸序列及其在改良植物代谢中的应用 |
| EP2100962A1 (en) | 2008-03-12 | 2009-09-16 | Biogemma | Plants having improved resistance to pathogens |
| CN103458715B (zh) * | 2010-08-05 | 2017-11-03 | 奥驰亚客户服务公司 | 一种无烟烟草产品以及其使用和制作方法 |
| RU2013139871A (ru) * | 2011-02-28 | 2015-04-10 | Норт Каролина Стейт Юниверсити | Инбредные растения табака ncbex1f, ncbex1mc и nc ex90 |
| JO3752B1 (ar) | 2011-06-10 | 2021-01-31 | Schweitzer Mauduit Int Inc | مواد تبغ تحتوي على جسيمات دقيقة من كربونات الكالسيوم غير متساوية القياس |
| GB2501671A (en) * | 2012-03-08 | 2013-11-06 | British American Tobacco Co | Smoking article |
| CN102851290A (zh) * | 2012-06-30 | 2013-01-02 | 河南农业大学 | 烟碱生物合成odc基因启动子及其应用 |
| UA117105C2 (uk) * | 2012-08-28 | 2018-06-25 | Філіп Морріс Продактс С.А. | Тютюнова композиція, що містить квітки тютюну |
| CN102816852B (zh) * | 2012-08-30 | 2014-03-26 | 浙江中烟工业有限责任公司 | 一种早期预判不同品种烟草成熟期叶片生物碱相对含量的方法 |
| KR102253223B1 (ko) * | 2012-12-21 | 2021-05-21 | 필립모리스 프로덕츠 에스.에이. | 식물 내 담배 특이 니트로사민 감소 |
| US10375910B2 (en) * | 2013-03-15 | 2019-08-13 | Altria Client Services Llc | Development of tobacco varieties with no or significantly reduced anatabine content |
| EP3536171B1 (en) * | 2013-11-19 | 2021-10-27 | Altria Client Services LLC | High yielding tobacco with oriental tobacco characteristics |
| CA2959245A1 (en) * | 2014-09-26 | 2016-03-31 | Philip Morris Products S.A | Reducing tobacco specific nitrosamines through alteration of the nitrate assimilation pathway |
| RU2680562C2 (ru) * | 2014-09-30 | 2019-02-22 | Филип Моррис Продактс С.А. | Способ получения гомогенизированного табачного материала и гомогенизированный табачный материал |
| US10813381B2 (en) * | 2014-09-30 | 2020-10-27 | Philip Morris Products S.A. | Homogenized tobacco material and method of production of homogenized tobacco material |
| CN107613762A (zh) * | 2015-05-05 | 2018-01-19 | 北卡罗莱纳州立大学 | 减少烟草中的烟草特异性亚硝胺nnk的方法和组合物 |
| CN116250483B (zh) | 2015-06-26 | 2024-01-30 | 奥驰亚客户服务公司 | 用于生产烟草植物的组合物和方法以及具有改变的生物碱含量的制品 |
| CN106290690B (zh) * | 2016-09-30 | 2017-10-13 | 中国烟草总公司郑州烟草研究院 | 一种基于生物碱的烟草代谢组学中新鲜烟叶样品质量的判别方法 |
| EP3813567B1 (en) * | 2018-06-28 | 2022-11-23 | Philip Morris Products S.A. | Cartridge for an aerosol-generating system containing a nicotine source comprising a liquid nicotine formulation |
| US20200035118A1 (en) * | 2018-07-27 | 2020-01-30 | Joseph Pandolfino | Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes |
| US10897925B2 (en) | 2018-07-27 | 2021-01-26 | Joseph Pandolfino | Articles and formulations for smoking products and vaporizers |
| EP3721722A1 (en) * | 2019-04-12 | 2020-10-14 | Nerudia Limited | A method of manufacturing |
| BR112022004480A2 (pt) | 2019-09-12 | 2022-05-31 | Cabbacis Llc | Artigos e formulações para produtos para fumar e vaporizadores |
| WO2023036691A1 (en) * | 2021-09-10 | 2023-03-16 | Philip Morris Products S.A. | Modulating alkaloid profiles in nicotiana tabacum |
| CN114698867B (zh) * | 2022-04-08 | 2023-03-03 | 贵州黄果树金叶科技有限公司 | 一种精准成分再造烟叶制备方法及再造烟叶 |
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| JP2002516869A (ja) | 1998-06-05 | 2002-06-11 | レジェンド コート テクノロジーズ | モノアミンオキシダーゼ（ｍａｏ）阻害剤とその使用 |
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| CN1076185C (zh) | 1999-12-14 | 2001-12-19 | 张建祥 | 保健香烟 |
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| CA2420724A1 (en) | 2000-08-30 | 2002-03-07 | North Carolina State University | Transgenic plants containing molecular decoys that alter protein content therein |
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| KR20040019301A (ko) * | 2001-06-08 | 2004-03-05 | 벡터 토바코 리미티드 | 담배에서 니코틴 및 니트로사민 수준의 조절 |
| AU2002322435A1 (en) | 2001-08-09 | 2003-02-24 | Cibus Genetics | Non-transgenic herbicide resistant plants |
-
2004
- 2004-08-18 KR KR1020067003351A patent/KR20060128821A/ko not_active Application Discontinuation
- 2004-08-18 AP AP2006003550A patent/AP2265A/xx active
- 2004-08-18 EA EA200600449A patent/EA200600449A1/ru unknown
- 2004-08-18 EP EP04781495A patent/EP1675454A4/en not_active Withdrawn
- 2004-08-18 OA OA1200600058A patent/OA13241A/en unknown
- 2004-08-18 AU AU2004266694A patent/AU2004266694A1/en not_active Abandoned
- 2004-08-18 CA CA002535763A patent/CA2535763A1/en not_active Abandoned
- 2004-08-18 BR BRPI0413733-7A patent/BRPI0413733A/pt not_active Application Discontinuation
- 2004-08-18 US US10/568,290 patent/US9814258B2/en not_active Expired - Fee Related
- 2004-08-18 WO PCT/US2004/026815 patent/WO2005018307A1/en active Search and Examination
- 2004-08-18 JP JP2006524011A patent/JP2007502621A/ja active Pending
- 2004-08-18 CN CNA2004800239055A patent/CN1838878A/zh active Pending
- 2004-08-18 MX MXPA06001591A patent/MXPA06001591A/es active IP Right Grant
- 2004-08-19 AR ARP040102977A patent/AR045466A1/es active IP Right Grant
-
2006
- 2006-01-26 ZA ZA200600749A patent/ZA200600749B/xx unknown
-
2017
- 2017-11-10 US US15/809,505 patent/US20180153207A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9814258B2 (en) | 2017-11-14 |
| US20070034220A1 (en) | 2007-02-15 |
| BRPI0413733A (pt) | 2006-10-24 |
| CA2535763A1 (en) | 2005-03-03 |
| ZA200600749B (en) | 2007-03-28 |
| AP2265A (en) | 2011-08-01 |
| OA13241A (en) | 2007-01-31 |
| WO2005018307A1 (en) | 2005-03-03 |
| MXPA06001591A (es) | 2006-05-19 |
| AP2006003550A0 (en) | 2006-04-30 |
| EA200600449A1 (ru) | 2006-08-25 |
| CN1838878A (zh) | 2006-09-27 |
| EP1675454A1 (en) | 2006-07-05 |
| AU2004266694A1 (en) | 2005-03-03 |
| EP1675454A4 (en) | 2007-03-21 |
| US20180153207A1 (en) | 2018-06-07 |
| KR20060128821A (ko) | 2006-12-14 |
| JP2007502621A (ja) | 2007-02-15 |
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