AR011542A1 - Un procedimiento para la preparacion de derivados de benzofenona y un procedimiento para la preparacion de 3,4-dihidroxi-4'-metil-5-nitrobenzofenona. - Google Patents
Un procedimiento para la preparacion de derivados de benzofenona y un procedimiento para la preparacion de 3,4-dihidroxi-4'-metil-5-nitrobenzofenona.Info
- Publication number
- AR011542A1 AR011542A1 ARP980100218A ARP980100218A AR011542A1 AR 011542 A1 AR011542 A1 AR 011542A1 AR P980100218 A ARP980100218 A AR P980100218A AR P980100218 A ARP980100218 A AR P980100218A AR 011542 A1 AR011542 A1 AR 011542A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- procedure
- derivatives
- formula
- nitrobenzofenone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/16—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/81—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
- C07C49/784—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with all keto groups bound to a non-condensed ring
- C07C49/786—Benzophenone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para la preparacion de derivados de benzofenona, que comprende separar sales de compuestos de formula (I) en donde R1 es alquiloinferior y R2 es hidrogeno, alquilo inferior o halogeno, mediante cristalizacion selectiva de sales decompuestos de formula (II), en donde R1 yR2 tienen el significado antes indicado. Estos derivados sirven para la preparacion de compuestos de formula V que por desmetilacion dan compuestosfarmacéuticamente activos de la form ula VI.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97100930 | 1997-01-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR011542A1 true AR011542A1 (es) | 2000-08-30 |
Family
ID=8226392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980100218A AR011542A1 (es) | 1997-01-22 | 1998-01-19 | Un procedimiento para la preparacion de derivados de benzofenona y un procedimiento para la preparacion de 3,4-dihidroxi-4'-metil-5-nitrobenzofenona. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5877353A (es) |
EP (1) | EP0855379B1 (es) |
JP (1) | JP2888814B2 (es) |
KR (1) | KR100268545B1 (es) |
CN (1) | CN1092178C (es) |
AR (1) | AR011542A1 (es) |
AT (1) | ATE205177T1 (es) |
AU (1) | AU733422B2 (es) |
BR (1) | BR9800426B1 (es) |
CA (1) | CA2227131C (es) |
DE (1) | DE69801532T2 (es) |
DK (1) | DK0855379T3 (es) |
ES (1) | ES2162351T3 (es) |
ID (1) | ID19540A (es) |
PT (1) | PT855379E (es) |
TR (1) | TR199800068A3 (es) |
ZA (1) | ZA98347B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6818776B2 (en) | 2000-02-01 | 2004-11-16 | Kyorin Pharmaceutical Co., Ltd. | Alkali metal salt of thiazolidine-2,4-dione derivative |
KR20040026964A (ko) * | 2002-09-27 | 2004-04-01 | 금호석유화학 주식회사 | 1,3-부타디엔과 아크릴산으로부터 시클로헥실 페닐 케톤의제조방법 |
EP1630600A3 (en) * | 2004-07-29 | 2006-03-22 | Rohm and Haas Electronic Materials, L.L.C. | Hot melt composition and method involving forming a masking pattern |
CN112601513B (zh) * | 2018-04-05 | 2023-12-22 | 普莱克斯医药公司 | 治疗眼部疾病的药物 |
CN108586224B (zh) * | 2018-06-27 | 2021-05-25 | 天津大学 | 一种二苯甲酮纯化分离的方法 |
CN116963727A (zh) * | 2020-11-13 | 2023-10-27 | 普莱克斯医药公司 | 用于治疗眼部病症的药剂 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK175069B1 (da) * | 1986-03-11 | 2004-05-24 | Hoffmann La Roche | Pyrocatecholderivater |
US5236952A (en) * | 1986-03-11 | 1993-08-17 | Hoffmann-La Roche Inc. | Catechol derivatives |
DE3643403A1 (de) * | 1986-12-19 | 1988-06-30 | Shell Agrar Gmbh & Co Kg | Benzophenone und verfahren zu ihrer herstellung |
-
1997
- 1997-04-15 ID IDP971255A patent/ID19540A/id unknown
-
1998
- 1998-01-15 DK DK98100582T patent/DK0855379T3/da active
- 1998-01-15 DE DE69801532T patent/DE69801532T2/de not_active Expired - Lifetime
- 1998-01-15 AT AT98100582T patent/ATE205177T1/de active
- 1998-01-15 CA CA002227131A patent/CA2227131C/en not_active Expired - Lifetime
- 1998-01-15 US US09/007,612 patent/US5877353A/en not_active Expired - Lifetime
- 1998-01-15 EP EP98100582A patent/EP0855379B1/en not_active Expired - Lifetime
- 1998-01-15 ES ES98100582T patent/ES2162351T3/es not_active Expired - Lifetime
- 1998-01-15 PT PT98100582T patent/PT855379E/pt unknown
- 1998-01-15 ZA ZA98347A patent/ZA98347B/xx unknown
- 1998-01-16 TR TR1998/00068A patent/TR199800068A3/tr unknown
- 1998-01-16 AU AU52102/98A patent/AU733422B2/en not_active Ceased
- 1998-01-19 AR ARP980100218A patent/AR011542A1/es active IP Right Grant
- 1998-01-20 JP JP10008558A patent/JP2888814B2/ja not_active Expired - Fee Related
- 1998-01-20 KR KR1019980001483A patent/KR100268545B1/ko not_active IP Right Cessation
- 1998-01-21 CN CN98104299A patent/CN1092178C/zh not_active Expired - Fee Related
- 1998-01-21 BR BRPI9800426-3A patent/BR9800426B1/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69801532D1 (de) | 2001-10-11 |
JPH10204021A (ja) | 1998-08-04 |
CN1092178C (zh) | 2002-10-09 |
BR9800426A (pt) | 1999-09-08 |
KR100268545B1 (ko) | 2000-10-16 |
MX9800608A (es) | 1998-10-31 |
TR199800068A2 (xx) | 1998-08-21 |
AU5210298A (en) | 1998-07-30 |
US5877353A (en) | 1999-03-02 |
ATE205177T1 (de) | 2001-09-15 |
EP0855379A1 (en) | 1998-07-29 |
DK0855379T3 (da) | 2001-12-17 |
AU733422B2 (en) | 2001-05-17 |
CA2227131A1 (en) | 1998-07-22 |
PT855379E (pt) | 2002-01-30 |
JP2888814B2 (ja) | 1999-05-10 |
ZA98347B (en) | 1998-07-22 |
CA2227131C (en) | 2008-10-07 |
ES2162351T3 (es) | 2001-12-16 |
EP0855379B1 (en) | 2001-09-05 |
KR19980070613A (ko) | 1998-10-26 |
DE69801532T2 (de) | 2002-05-23 |
CN1188755A (zh) | 1998-07-29 |
ID19540A (id) | 1998-07-23 |
BR9800426B1 (pt) | 2010-05-18 |
TR199800068A3 (tr) | 1998-08-21 |
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Legal Events
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FG | Grant, registration |