AR009958A1 - ADJUVANT COMPOSITIONS; VACCINES FORMULATED WITH SUCH COMPOSITIONS; THE USE OF SUCH COMPOSITIONS IN THE PREPARATION OF VACCINES AND PROCEDURE FOR PREPARING SUCH VACCINES. - Google Patents
ADJUVANT COMPOSITIONS; VACCINES FORMULATED WITH SUCH COMPOSITIONS; THE USE OF SUCH COMPOSITIONS IN THE PREPARATION OF VACCINES AND PROCEDURE FOR PREPARING SUCH VACCINES.Info
- Publication number
- AR009958A1 AR009958A1 ARP970104569A ARP970104569A AR009958A1 AR 009958 A1 AR009958 A1 AR 009958A1 AR P970104569 A ARP970104569 A AR P970104569A AR P970104569 A ARP970104569 A AR P970104569A AR 009958 A1 AR009958 A1 AR 009958A1
- Authority
- AR
- Argentina
- Prior art keywords
- vaccines
- compositions
- preparation
- formulated
- preparing
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/11011—Alpharetrovirus, e.g. avian leucosis virus
- C12N2740/11034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Se trata de composiciones adyuvantes, formuladas con alumbre, fracciones de saponinas inmunologicamente activas, y un esterol, particularmente colesterol.De preferencia, se trata de saponinas provenientes de la corteza de Quillaja SaponariaMolin a, tal como la fraccion Q21. También se proponen vacunas queincluyen dichas composiciones adyuvantes, para el tratamiento de enfermos de cancer o el tratamiento profilactico de infecciones. También se reivindica lapreparacion de dichasvacunas y l a preparacion de las composiciones adyuvantes mencionadas.These are adjuvant compositions, formulated with alum, immunologically active saponin fractions, and a sterol, particularly cholesterol. Preferably, they are saponins from the bark of Quillaja SaponariaMolin a, such as fraction Q21. Vaccines including such adjuvant compositions are also proposed, for the treatment of cancer patients or the prophylactic treatment of infections. The preparation of said vaccines and the preparation of the mentioned adjuvant compositions are also claimed.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9620795.6A GB9620795D0 (en) | 1996-10-05 | 1996-10-05 | Vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
AR009958A1 true AR009958A1 (en) | 2000-05-17 |
Family
ID=10800990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970104569A AR009958A1 (en) | 1996-10-05 | 1997-10-03 | ADJUVANT COMPOSITIONS; VACCINES FORMULATED WITH SUCH COMPOSITIONS; THE USE OF SUCH COMPOSITIONS IN THE PREPARATION OF VACCINES AND PROCEDURE FOR PREPARING SUCH VACCINES. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0939650A1 (en) |
JP (1) | JP2001501640A (en) |
KR (1) | KR20000048866A (en) |
CN (1) | CN1238696A (en) |
AR (1) | AR009958A1 (en) |
AU (1) | AU714930B2 (en) |
BR (1) | BR9711853A (en) |
CA (1) | CA2267191A1 (en) |
CO (1) | CO4910170A1 (en) |
CZ (1) | CZ116799A3 (en) |
GB (1) | GB9620795D0 (en) |
HU (1) | HUP9904549A3 (en) |
IL (1) | IL128985A0 (en) |
NO (1) | NO991524D0 (en) |
NZ (1) | NZ334734A (en) |
PL (1) | PL332633A1 (en) |
TR (1) | TR199900729T2 (en) |
WO (1) | WO1998015287A1 (en) |
ZA (1) | ZA978868B (en) |
Families Citing this family (69)
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CA2654522C (en) * | 1997-08-29 | 2014-01-28 | Antigenics Inc. | Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as exipient |
GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
GB9817052D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
EP1588714A2 (en) * | 1998-10-16 | 2005-10-26 | GlaxoSmithKline Biologicals S.A. | Adjuvant systems and vaccines |
AU769539B2 (en) | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
GB9909077D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
CZ303515B6 (en) | 1999-04-19 | 2012-11-07 | Smithkline Beecham Biologicals S. A. | Adjuvant compositions |
US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
GB9921147D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
ATE291008T1 (en) | 1999-09-24 | 2005-04-15 | Nihon Nohyaku Co Ltd | AROMATIC DIAMIDE DERIVATIVES OR SALTS THEIR, AGRICULTURAL/HORTICULTURE CHEMICALS AND METHOD FOR USE THEREOF |
AU1013601A (en) | 1999-10-22 | 2001-05-08 | Aventis Pasteur Limited | Method of inducing and/or enhancing an immune response to tumor antigens |
WO2001037869A1 (en) * | 1999-11-19 | 2001-05-31 | Csl Limited | Vaccine compositions |
EP1235591A1 (en) * | 1999-12-08 | 2002-09-04 | Statens Veterinärmedicinska Anstalt | Vaccine adjuvants comprising ginseng plant extract and added aluminium salt |
US6905712B2 (en) | 1999-12-08 | 2005-06-14 | Statens Veterinarmedicinska Anstalt | Vaccine adjuvants comprising ginseng plant extract and added aluminum salt |
ATE346925T1 (en) | 2000-05-10 | 2006-12-15 | Sanofi Pasteur Ltd | IMMUNOGENIC POLYPEPTIDES ENCODED BY MAGE MINIGENE AND USES THEREOF |
ES2392943T3 (en) | 2000-10-18 | 2012-12-17 | Glaxosmithkline Biologicals S.A. | Anti-tumor vaccines |
WO2002074336A2 (en) * | 2001-02-23 | 2002-09-26 | Glaxosmithkline Biologicals S.A. | Influenza vaccine formulations for intradermal delivery |
US20040096463A1 (en) * | 2001-02-23 | 2004-05-20 | Nathalie Garcon | Novel vaccine |
GB0110431D0 (en) * | 2001-04-27 | 2001-06-20 | Glaxosmithkline Biolog Sa | Novel compounds |
GB0123580D0 (en) * | 2001-10-01 | 2001-11-21 | Glaxosmithkline Biolog Sa | Vaccine |
AU2003254585A1 (en) | 2002-07-24 | 2004-02-16 | Intercell Ag | Antigens encoded by alternative reading frame from pathogenic viruses |
JP2006504687A (en) | 2002-09-13 | 2006-02-09 | インターツェル・アクチェンゲゼルシャフト | Method for isolating hepatitis C virus peptide |
ES2594758T3 (en) | 2002-10-23 | 2016-12-22 | Glaxosmithkline Biologicals S.A. | Vaccination procedures against malaria |
WO2004084937A1 (en) * | 2003-03-24 | 2004-10-07 | Intercell Ag | Use of alum and a th1 immune response inducing adjuvant for enhancing immune responses |
ATE485056T1 (en) | 2003-03-24 | 2010-11-15 | Intercell Ag | IMPROVED VACCINES |
GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
GB0513421D0 (en) | 2005-06-30 | 2005-08-03 | Glaxosmithkline Biolog Sa | Vaccines |
GB0519871D0 (en) | 2005-09-30 | 2005-11-09 | Secr Defence | Immunogenic agents |
US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
JP2009514838A (en) | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | Adjuvant vaccine containing non-virion antigen prepared from influenza virus grown in cell culture |
TWI457133B (en) * | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | Novel composition |
TW201350129A (en) | 2005-12-22 | 2013-12-16 | Glaxosmithkline Biolog Sa | Streptococcus pneumoniae immunogenic composition comprising capsular saccharide conjugates, vaccine and kit comprising the same and uses thereof |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
CA2647441C (en) | 2006-03-30 | 2021-02-23 | Glaxosmithkline Biologicals S.A. | Immunogenic composition comprising staphylococcus aureus saccharides |
US9364525B2 (en) | 2006-07-18 | 2016-06-14 | Glaxosmithkline Biologicals Sa | Vaccines for malaria |
GB2453475B (en) | 2006-07-25 | 2011-01-19 | Secr Defence | Live vaccine strain |
AU2007322424B2 (en) * | 2006-11-20 | 2013-05-16 | Duecom | Use of lipid containing particles comprising quillaja saponins for the treatment of cancer |
CA2896131C (en) | 2007-03-02 | 2020-04-07 | Glaxosmithkline Biologicals S.A. | Novel method and compositions |
AU2008267208B2 (en) | 2007-06-26 | 2012-01-19 | Glaxosmithkline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
UY31285A1 (en) | 2007-08-13 | 2009-03-31 | VACCINES | |
US10040825B2 (en) | 2007-12-19 | 2018-08-07 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Soluble forms of Hendra and Nipah virus F glycoprotein and uses thereof |
GB0815872D0 (en) | 2008-09-01 | 2008-10-08 | Pasteur Institut | Novel method and compositions |
GB0900455D0 (en) | 2009-01-13 | 2009-02-11 | Secr Defence | Vaccine |
GB0901411D0 (en) | 2009-01-29 | 2009-03-11 | Secr Defence | Treatment |
GB0901423D0 (en) | 2009-01-29 | 2009-03-11 | Secr Defence | Treatment |
ES2608841T3 (en) | 2009-02-10 | 2017-04-17 | Seqirus UK Limited | Flu shots with reduced amounts of squalene |
AU2010220824A1 (en) * | 2009-03-05 | 2011-10-20 | Jenny Colleen Mccloskey | Treatment of infection |
GB0906234D0 (en) | 2009-04-14 | 2009-05-20 | Secr Defence | Vaccine |
GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
WO2011117408A1 (en) | 2010-03-26 | 2011-09-29 | Glaxosmithkline Biologicals S.A. | Hiv vaccine |
US20130259948A1 (en) | 2010-09-21 | 2013-10-03 | National Institute Of Immunology | Spray dried powder formulation for vaccines entrapping alum and the antigen in biodegradable polymer particles |
BR112013004582A2 (en) | 2010-09-27 | 2016-09-06 | Crucell Holland Bv | method for inducing an immune response in a subject against a parasite antigen that causes malaria |
SI2758432T1 (en) | 2011-09-16 | 2019-07-31 | Ucb Biopharma Sprl | Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile |
WO2013074501A1 (en) | 2011-11-14 | 2013-05-23 | Crucell Holland B.V. | Heterologous prime-boost immunization using measles virus-based vaccines |
WO2015092710A1 (en) | 2013-12-19 | 2015-06-25 | Glaxosmithkline Biologicals, S.A. | Contralateral co-administration of vaccines |
BR112019003462A2 (en) | 2016-08-23 | 2019-06-25 | Glaxosmithkline Biologicals Sa | fusion protein, polynucleotide, viral vector, pharmaceutical composition, use of a fusion protein, polynucleotide, viral vector or pharmaceutical composition, and method for treating or preventing viral hepatitis b infection or viral hepatitis c infection |
GB201614799D0 (en) | 2016-09-01 | 2016-10-19 | Glaxosmithkline Biologicals Sa | Compositions |
BE1024774B1 (en) | 2016-09-29 | 2018-07-02 | Glaxosmithkline Biologicals Sa | COMPOSITIONS AND METHODS OF TREATMENT |
BE1025160B1 (en) * | 2016-12-07 | 2018-11-26 | Glaxosmithkline Biologicals Sa | NEW PROCESS |
GB201620968D0 (en) | 2016-12-09 | 2017-01-25 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
BR112019025193A2 (en) * | 2017-05-30 | 2020-06-23 | Glaxosmithkline Biologicals S.A. | METHODS OF MANUFACTURING A LIPOSOMAL ADJUVANT, MANUFACTURING A LIPOSOMAL CONCENTRATE, FOR THE PREPARATION OF AN IMMUNOGENIC COMPOSITION WITH ADJUVANT AND FOR THE PREPARATION OF A SOLUTION, LIPOSOMAL ADJUVANT, IMMUNOGENOUS COMPOUND, WITH SOLUTION, |
GB201721068D0 (en) | 2017-12-15 | 2018-01-31 | Glaxosmithkline Biologicals Sa | Hepatitis B immunisation regimen and compositions |
GB201721069D0 (en) | 2017-12-15 | 2018-01-31 | Glaxosmithkline Biologicals Sa | Hepatitis B Immunisation regimen and compositions |
US11702674B2 (en) | 2018-06-12 | 2023-07-18 | Glaxosmithkline Biologicals Sa | Simian adenovirus vectors comprising the ChAd-157 fiber protein |
BR112021000965A2 (en) | 2018-08-07 | 2021-04-27 | Glaxosmithkline Biologicals S.A. | processes and vaccines |
US20220184158A1 (en) | 2018-12-21 | 2022-06-16 | Glaxosmithkline Biologicals Sa | Methods of inducing an immune response |
CN113573730A (en) | 2019-03-05 | 2021-10-29 | 葛兰素史密斯克莱生物公司 | Hepatitis B immunization protocols and compositions |
WO2023056117A1 (en) * | 2021-10-02 | 2023-04-06 | Massachusetts Institute Of Technology | Synergistic combination of alum and non-liposome, non-micelle particle vaccine adjuvants |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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NL9002314A (en) * | 1990-10-23 | 1992-05-18 | Nederlanden Staat | IMMUNOGENE COMPLEXES, IN PARTICULAR ISCOMS. |
IL102639A (en) * | 1991-07-25 | 1997-03-18 | Idec Pharma Corp | Compositions for inducing cytotoxic t lymphocyte responses |
DE69432665T3 (en) * | 1993-03-29 | 2007-12-06 | Pfizer Inc. | MULTICOMPONENT VACCINE FROM CLOSTRIDIA USING SAPONINE AS ADJUVANS |
UA56132C2 (en) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Vaccine composition (variants), method for stabilizing qs21 providing resistance against hydrolysis (variants), method for manufacturing vaccine |
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1996
- 1996-10-05 GB GBGB9620795.6A patent/GB9620795D0/en active Pending
-
1997
- 1997-09-30 BR BR9711853A patent/BR9711853A/en not_active Application Discontinuation
- 1997-09-30 CZ CZ991167A patent/CZ116799A3/en unknown
- 1997-09-30 WO PCT/EP1997/005578 patent/WO1998015287A1/en not_active Application Discontinuation
- 1997-09-30 TR TR1999/00729T patent/TR199900729T2/en unknown
- 1997-09-30 JP JP10517196A patent/JP2001501640A/en active Pending
- 1997-09-30 PL PL97332633A patent/PL332633A1/en unknown
- 1997-09-30 CA CA002267191A patent/CA2267191A1/en not_active Abandoned
- 1997-09-30 HU HU9904549A patent/HUP9904549A3/en unknown
- 1997-09-30 KR KR1019990702874A patent/KR20000048866A/en not_active Application Discontinuation
- 1997-09-30 NZ NZ334734A patent/NZ334734A/en unknown
- 1997-09-30 EP EP97910430A patent/EP0939650A1/en not_active Withdrawn
- 1997-09-30 IL IL12898597A patent/IL128985A0/en unknown
- 1997-09-30 AU AU47812/97A patent/AU714930B2/en not_active Ceased
- 1997-09-30 CN CN97180166A patent/CN1238696A/en active Pending
- 1997-10-03 ZA ZA978868A patent/ZA978868B/en unknown
- 1997-10-03 CO CO97057863A patent/CO4910170A1/en unknown
- 1997-10-03 AR ARP970104569A patent/AR009958A1/en unknown
-
1999
- 1999-03-29 NO NO991524A patent/NO991524D0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1238696A (en) | 1999-12-15 |
PL332633A1 (en) | 1999-09-27 |
WO1998015287A1 (en) | 1998-04-16 |
HU9904549A (en) | 2000-05-28 |
JP2001501640A (en) | 2001-02-06 |
GB9620795D0 (en) | 1996-11-20 |
AU714930B2 (en) | 2000-01-13 |
ZA978868B (en) | 1999-04-06 |
EP0939650A1 (en) | 1999-09-08 |
BR9711853A (en) | 1999-08-24 |
AU4781297A (en) | 1998-05-05 |
CO4910170A1 (en) | 2000-04-24 |
TR199900729T2 (en) | 1999-07-21 |
NZ334734A (en) | 2000-05-26 |
NO991524L (en) | 1999-03-29 |
KR20000048866A (en) | 2000-07-25 |
CA2267191A1 (en) | 1998-04-16 |
HUP9904549A3 (en) | 2001-06-28 |
CZ116799A3 (en) | 1999-08-11 |
NO991524D0 (en) | 1999-03-29 |
IL128985A0 (en) | 2000-02-17 |
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