AR006283A1 - Derivados de indazol 1,3,5-trisustituidos provistos de un efecto anti- asmatico, anti-alergico, inhibidor de las inflamaciones de inmuno-modulador,procedimiento para su preparacion y su utilizacion como medicamento - Google Patents
Derivados de indazol 1,3,5-trisustituidos provistos de un efecto anti- asmatico, anti-alergico, inhibidor de las inflamaciones de inmuno-modulador,procedimiento para su preparacion y su utilizacion como medicamentoInfo
- Publication number
- AR006283A1 AR006283A1 ARP970101088A ARP970101088A AR006283A1 AR 006283 A1 AR006283 A1 AR 006283A1 AR P970101088 A ARP970101088 A AR P970101088A AR P970101088 A ARP970101088 A AR P970101088A AR 006283 A1 AR006283 A1 AR 006283A1
- Authority
- AR
- Argentina
- Prior art keywords
- asthmatic
- preparation
- trisustitued
- inflammations
- indazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen derivados de indazol 1,3,5-trisustituidos de la fórmula general (I), poseen un efecto anti-asmático, anti-alérgico, inhibidor de lasinflamaciones y/o inmunomodulador, y son adecuados para la preparación de medicamentos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19610882A DE19610882A1 (de) | 1996-03-20 | 1996-03-20 | Neue 1,3,5-trisubstituierte Indazol-Derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
AR006283A1 true AR006283A1 (es) | 1999-08-11 |
Family
ID=7788810
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970101088A AR006283A1 (es) | 1996-03-20 | 1997-03-19 | Derivados de indazol 1,3,5-trisustituidos provistos de un efecto anti- asmatico, anti-alergico, inhibidor de las inflamaciones de inmuno-modulador,procedimiento para su preparacion y su utilizacion como medicamento |
Country Status (10)
Country | Link |
---|---|
US (1) | US5776932A (es) |
EP (1) | EP0888307A1 (es) |
JP (1) | JP2000506874A (es) |
AR (1) | AR006283A1 (es) |
AU (1) | AU2025697A (es) |
BR (1) | BR9709444A (es) |
CA (1) | CA2200385A1 (es) |
DE (1) | DE19610882A1 (es) |
WO (1) | WO1997034874A1 (es) |
ZA (1) | ZA971883B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0816357B1 (en) * | 1996-06-27 | 2002-01-09 | Pfizer Inc. | Substituted indazole derivatives |
DE19821002A1 (de) * | 1998-05-11 | 1999-11-18 | Dresden Arzneimittel | Neue 1,5- und 3-O-substituierte 1H-Indazole mit antiasthmatischer, antiallergischer, entzündungshemmender, immunmodulierender und neuroprotektiver Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE19821003A1 (de) | 1998-05-11 | 1999-11-18 | Dresden Arzneimittel | Neue 1,2,5-trisubstituierte 1,2-dihydro-indazol-3-one mit antiasthmatischer, antiallergischer, entzündungshemmender, immunmodulierender und neuroprotektiver Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US6169185B1 (en) | 1999-02-25 | 2001-01-02 | Day-Glo Color Corp. | Ink jet printing inks |
DE10007203A1 (de) * | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
WO2003035005A2 (en) * | 2001-10-26 | 2003-05-01 | University Of Connecticut | Heteroindanes: a new class of potent cannabimimetic ligands |
TW200505913A (en) | 2003-03-28 | 2005-02-16 | Hoffmann La Roche | Novel oxazole derivatives, their manufacture and use as pharmaceutical agents |
US7582631B2 (en) * | 2004-01-14 | 2009-09-01 | Amgen Inc. | Substituted heterocyclic compounds and methods of use |
US8034940B2 (en) | 2006-08-09 | 2011-10-11 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
WO2009071483A1 (en) * | 2007-12-07 | 2009-06-11 | Via Pharmaceuticals, Inc. | 1- (indaz0l-5-yl) -ureas as diacylglycerol acyltransferase inhibitors |
US10500178B2 (en) | 2015-03-13 | 2019-12-10 | The Board Of Trustees Of The Leland Stanford Junior University | LTB4 inhibition to prevent and treat human lymphedema |
CN115197117B (zh) * | 2022-05-17 | 2023-09-15 | 沈阳化工大学 | 抑制金黄色葡萄球菌胱硫醚-γ-裂解酶的吲哚类衍生物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1054833A (es) * | 1963-08-09 | |||
IL28032A (en) * | 1966-08-29 | 1971-08-25 | Acraf | Indazol-3-yl-oxyalkanoic acids and process for the preparation thereof |
GB1152885A (en) * | 1966-08-29 | 1969-05-21 | Acraf | Indazole-3-yl-Oxyalkanoic Acids and process for the preparation thereof |
US3625970A (en) * | 1968-04-17 | 1971-12-07 | Cutter Lab | 1-(disubstituted phenyl or benzyl)-1h-indazol-3-yloxyacetic acid |
GB1435943A (en) * | 1973-02-07 | 1976-05-19 | Delmar Chem | Indazole-derived tertiary amines |
US4537966A (en) * | 1983-12-22 | 1985-08-27 | Pennwalt Corporation | 1-(Aminobenzoyl)-1H-indazol-3-ols |
EP0191520B1 (en) * | 1985-02-12 | 1989-06-21 | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. | (1-phenylmethyl-5-hydroxy-1h-indazol-3-yl)-oxyacetic acid and salts thereof for use as a medicament, and pharmaceutical compositions containing them |
GB8607294D0 (en) * | 1985-04-17 | 1986-04-30 | Ici America Inc | Heterocyclic amide derivatives |
IE910278A1 (en) * | 1990-02-16 | 1991-08-28 | Ici Plc | Heterocyclic compounds |
US5334597A (en) * | 1991-10-17 | 1994-08-02 | Merck Frosst Canada, Inc. | Indole carbamates as leukotriene antagonists |
DE4224363A1 (de) * | 1992-07-23 | 1994-01-27 | Henkel Kgaa | Nitroindazolinone als Färbemittel für Fasern natürlichen Ursprungs und synthetische Fasern |
NO940245D0 (no) * | 1993-01-28 | 1994-01-24 | Takeda Chemical Industries Ltd | Quinolin eller quinazolinderivater, deres fremstilling og anvendelse |
-
1996
- 1996-03-20 DE DE19610882A patent/DE19610882A1/de not_active Withdrawn
-
1997
- 1997-03-05 ZA ZA9701883A patent/ZA971883B/xx unknown
- 1997-03-07 JP JP9533094A patent/JP2000506874A/ja active Pending
- 1997-03-07 BR BR9709444A patent/BR9709444A/pt not_active Application Discontinuation
- 1997-03-07 EP EP97908199A patent/EP0888307A1/de not_active Withdrawn
- 1997-03-07 AU AU20256/97A patent/AU2025697A/en not_active Abandoned
- 1997-03-07 WO PCT/EP1997/001166 patent/WO1997034874A1/de not_active Application Discontinuation
- 1997-03-19 CA CA002200385A patent/CA2200385A1/en not_active Abandoned
- 1997-03-19 AR ARP970101088A patent/AR006283A1/es unknown
- 1997-03-20 US US08/821,740 patent/US5776932A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5776932A (en) | 1998-07-07 |
AU2025697A (en) | 1997-10-10 |
JP2000506874A (ja) | 2000-06-06 |
EP0888307A1 (de) | 1999-01-07 |
DE19610882A1 (de) | 1997-09-25 |
CA2200385A1 (en) | 1997-09-20 |
BR9709444A (pt) | 1999-08-10 |
WO1997034874A1 (de) | 1997-09-25 |
ZA971883B (en) | 1997-11-10 |
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