AP201508963A0 - Genetically sterile animals - Google Patents

Genetically sterile animals

Info

Publication number
AP201508963A0
AP201508963A0 AP201508963A AP201508963A AP201508963A0 AP 201508963 A0 AP201508963 A0 AP 201508963A0 AP 201508963 A AP201508963 A AP 201508963A AP 201508963 A AP201508963 A AP 201508963A AP 201508963 A0 AP201508963 A0 AP 201508963A0
Authority
AP
ARIPO
Prior art keywords
sterile animals
genetically sterile
genetically
animals
Prior art date
Application number
AP201508963A
Inventor
Daniel F Carlson
Scott C Fahrenkrug
Original Assignee
Recombinetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201361829656P priority Critical
Priority to US201361870558P priority
Application filed by Recombinetics Inc filed Critical Recombinetics Inc
Priority to PCT/US2014/035847 priority patent/WO2014193583A2/en
Publication of AP201508963A0 publication Critical patent/AP201508963A0/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027New breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knockout animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027New breeds of vertebrates
    • A01K67/0273Cloned animals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A01K2217/077Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out heterozygous knock out animals displaying phenotype
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/101Bovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/103Ovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/108Swine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/80Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites
AP201508963A 2013-05-31 2014-04-29 Genetically sterile animals AP201508963A0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US201361829656P true 2013-05-31 2013-05-31
US201361870558P true 2013-08-27 2013-08-27
PCT/US2014/035847 WO2014193583A2 (en) 2013-05-31 2014-04-29 Genetically sterile animals

Publications (1)

Publication Number Publication Date
AP201508963A0 true AP201508963A0 (en) 2016-01-31

Family

ID=51986779

Family Applications (1)

Application Number Title Priority Date Filing Date
AP201508963A AP201508963A0 (en) 2013-05-31 2014-04-29 Genetically sterile animals

Country Status (13)

Country Link
US (2) US20140359796A1 (en)
EP (1) EP3004345A4 (en)
JP (1) JP2016525890A (en)
KR (1) KR20160013219A (en)
CN (1) CN105473714A (en)
AP (1) AP201508963A0 (en)
AU (1) AU2014272106A1 (en)
BR (1) BR112015029904A2 (en)
CA (1) CA2913411A1 (en)
MX (1) MX2015016385A (en)
PH (1) PH12015502640A1 (en)
RU (1) RU2015156801A (en)
WO (1) WO2014193583A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3613852A3 (en) 2011-07-22 2020-04-22 President and Fellows of Harvard College Evaluation and improvement of nuclease cleavage specificity
US9163284B2 (en) 2013-08-09 2015-10-20 President And Fellows Of Harvard College Methods for identifying a target site of a Cas9 nuclease
US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
US9526784B2 (en) 2013-09-06 2016-12-27 President And Fellows Of Harvard College Delivery system for functional nucleases
US9340800B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College Extended DNA-sensing GRNAS
US20150166982A1 (en) 2013-12-12 2015-06-18 President And Fellows Of Harvard College Methods for correcting pi3k point mutations
US9745561B2 (en) * 2014-01-08 2017-08-29 Iowa State University Research Foundation, Inc. Genetic test and genetic basis for SCID in pigs
AU2015289799B2 (en) * 2014-07-14 2018-07-26 The University Court Of The University Of Edinburgh NANOS knock-out that ablates germline cells
EP3177718A4 (en) 2014-07-30 2018-04-04 President and Fellows of Harvard College Cas9 proteins including ligand-dependent inteins
WO2017062756A1 (en) * 2015-10-07 2017-04-13 Recombinetics, Inc. Method of generating sterile terminal sires in livestock and animals produced thereby
SG11201803173VA (en) 2015-10-23 2018-05-30 Harvard College Nucleobase editors and uses thereof
CN105543257A (en) * 2016-01-18 2016-05-04 安徽农业大学 PAPN gene site-directed modified pig
AU2017306676A1 (en) 2016-08-03 2019-02-28 President And Fellows Of Harard College Adenosine nucleobase editors and uses thereof
WO2019165465A1 (en) * 2018-02-26 2019-08-29 Aggenetics, Inc. Materials and methods for preventing transmission of a particular chromosome
GB201816633D0 (en) * 2018-10-12 2018-11-28 Univ Court Of The Univ Of Edinburgh Genetically modified avians and method for the reconstitution thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069257A2 (en) * 1999-05-13 2000-11-23 Cedars-Sinai Medical Center Genetic modification of male germ cells for generation of transgenic species and genetic therapies
IL151453D0 (en) * 2000-02-24 2003-04-10 Univ Massachusetts Production of mammals which produce progeny of a single sex
WO2002077637A1 (en) * 2001-03-22 2002-10-03 Infigen, Inc. Sex-specific selection of sperm from transgenic animals
US20050125853A1 (en) * 2002-03-22 2005-06-09 St. Jude Children's Resarch Hospital Method for generating genetically modified animals
US8735156B2 (en) * 2008-12-01 2014-05-27 The Board Of Regents Of The University Of Texas System Production and use of rat spermatogonial stem cell lines
JP2013500018A (en) * 2009-07-24 2013-01-07 シグマ−アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニーSigma−Aldrich Co., LLC Methods for genome editing
WO2011023740A1 (en) * 2009-08-28 2011-03-03 Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research Genetic vasectomy by overexpression of prml-egfp fusion protein in spermatids
KR20140046408A (en) * 2011-02-25 2014-04-18 리컴비네틱스 인코포레이티드 Genetically modified animals and methods for making the same
WO2012158985A2 (en) * 2011-05-17 2012-11-22 Transposagen Biopharmaceuticals, Inc. Methods for site-specific genetic modification in spermatogonial stem cells using zinc finger nuclease (zfn) for the creation of model organisms
KR20150100651A (en) * 2012-10-30 2015-09-02 리컴비네틱스 인코포레이티드 Control of sexual maturation in animals
US20140359795A1 (en) * 2013-05-31 2014-12-04 Recombinetics, Inc. Genetic techniques for making animals with sortable sperm

Also Published As

Publication number Publication date
MX2015016385A (en) 2016-04-11
AU2014272106A1 (en) 2016-01-21
CA2913411A1 (en) 2014-12-04
US20140359796A1 (en) 2014-12-04
WO2014193583A2 (en) 2014-12-04
BR112015029904A2 (en) 2017-09-26
EP3004345A2 (en) 2016-04-13
WO2014193583A3 (en) 2015-01-22
RU2015156801A (en) 2017-07-06
CN105473714A (en) 2016-04-06
US20190335725A1 (en) 2019-11-07
PH12015502640A1 (en) 2016-03-07
JP2016525890A (en) 2016-09-01
EP3004345A4 (en) 2017-02-15
KR20160013219A (en) 2016-02-03

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