WO2004101775A1 - 新規な成体組織由来の幹細胞およびその用途 - Google Patents
新規な成体組織由来の幹細胞およびその用途 Download PDFInfo
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- WO2004101775A1 WO2004101775A1 PCT/JP2004/006912 JP2004006912W WO2004101775A1 WO 2004101775 A1 WO2004101775 A1 WO 2004101775A1 JP 2004006912 W JP2004006912 W JP 2004006912W WO 2004101775 A1 WO2004101775 A1 WO 2004101775A1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005506274A JPWO2004101775A1 (ja) | 2003-05-16 | 2004-05-14 | 新規な成体組織由来の幹細胞およびその用途 |
EP04733177A EP1637589A4 (en) | 2003-05-16 | 2004-05-14 | NEW STEM CELL DERIVED FROM ADULT FABRIC AND THEIR USE |
US10/557,053 US20070053884A1 (en) | 2003-05-16 | 2004-05-14 | Novel adult tissue-derived stem cell and use thereof |
CA002525909A CA2525909A1 (en) | 2003-05-16 | 2004-05-14 | Novel stem cell derived from adult tissue and use thereof |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003139605 | 2003-05-16 | ||
JP2003-139605 | 2003-05-16 | ||
JP2003-351168 | 2003-10-09 | ||
JP2003351168 | 2003-10-09 | ||
JP2003419400 | 2003-12-17 | ||
JP2003-419400 | 2003-12-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004101775A1 true WO2004101775A1 (ja) | 2004-11-25 |
Family
ID=33458362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2004/006912 WO2004101775A1 (ja) | 2003-05-16 | 2004-05-14 | 新規な成体組織由来の幹細胞およびその用途 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070053884A1 (ja) |
EP (1) | EP1637589A4 (ja) |
JP (1) | JPWO2004101775A1 (ja) |
CA (1) | CA2525909A1 (ja) |
WO (1) | WO2004101775A1 (ja) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006123699A1 (ja) * | 2005-05-17 | 2006-11-23 | Kyowa Hakko Kogyo Co., Ltd. | 幹細胞に対する骨芽細胞への分化促進剤 |
JP2007105037A (ja) * | 2005-09-16 | 2007-04-26 | Univ Of Tokyo | キメリズムを利用した幹細胞移植のための検査 |
JPWO2006006692A1 (ja) * | 2004-07-08 | 2008-05-01 | 独立行政法人科学技術振興機構 | 低血清培養で選択的に増殖する動物組織遍在性の分化多能性細胞 |
US20100136681A1 (en) * | 2007-04-02 | 2010-06-03 | The General Hospital Corporation | Cellular compositions for the treatment of kidney disease and uses thereof |
WO2011034106A1 (ja) * | 2009-09-15 | 2011-03-24 | 株式会社資生堂 | 真皮幹細胞の単離方法 |
US10018630B2 (en) | 2011-09-07 | 2018-07-10 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell isolation |
US10934351B2 (en) | 2011-10-28 | 2021-03-02 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
US11124773B2 (en) | 2010-10-06 | 2021-09-21 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell population and method for production thereof |
US11536713B2 (en) | 2009-12-25 | 2022-12-27 | Chugai Seiyaku Kabushiki Kaisha | Method for searching and screening for target of anti-cancer agent using non-human animal model having NOG established cancer cell line transplanted therein |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1670414A4 (en) * | 2003-10-06 | 2007-09-26 | Cedars Sinai Medical Center | USE OF THE EXPRESSION OF CXCR4 PROTEIN ON THE SURFACE OF STEM CELLS AS A TUMORAL TROPICAL POTENTIAL MARKER |
US8129187B2 (en) * | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
EP4223769A3 (en) * | 2005-12-13 | 2023-11-01 | Kyoto University | Nuclear reprogramming factor |
US20090227032A1 (en) * | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
US8278104B2 (en) * | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
US9213999B2 (en) * | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
EP2268809B1 (en) * | 2008-05-02 | 2019-02-06 | Kyoto University | Method of nuclear reprogramming |
CA2725208A1 (en) * | 2008-05-06 | 2009-11-12 | Joslin Diabetes Center, Inc. | Methods and compositions for inducing brown adipogenesis |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001048151A1 (fr) * | 1999-12-28 | 2001-07-05 | Kyowa Hakko Kogyo Co., Ltd. | Cellules pouvant induire une differenciation dans des cellules du muscle cardiaque |
WO2002050243A2 (en) * | 2000-12-19 | 2002-06-27 | Insight Strategy And Marketing Ltd. | The use of ecm degrading enzymes for the improvement of cell transplantation |
JP2003506075A (ja) * | 1999-08-05 | 2003-02-18 | エムシーエル エルエルシー | 多能性成人幹細胞およびそれを単離する方法 |
JP2003052365A (ja) * | 2001-08-20 | 2003-02-25 | Japan Science & Technology Corp | 哺乳動物からの間葉系幹細胞の分離及びその利用方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL125532A0 (en) * | 1998-07-27 | 1999-03-12 | Yeda Res & Dev | Hematopoietic cell composition for use in transplantation |
US7811557B1 (en) * | 2000-10-27 | 2010-10-12 | Viacell, Inc. | Methods for improving central nervous system functioning |
AU2003290601A1 (en) * | 2002-11-05 | 2004-06-03 | The Brigham And Women's Hospital, Inc. | Mesenchymal stem cells and methods of use thereof |
-
2004
- 2004-05-14 US US10/557,053 patent/US20070053884A1/en not_active Abandoned
- 2004-05-14 EP EP04733177A patent/EP1637589A4/en not_active Withdrawn
- 2004-05-14 JP JP2005506274A patent/JPWO2004101775A1/ja active Pending
- 2004-05-14 WO PCT/JP2004/006912 patent/WO2004101775A1/ja active Application Filing
- 2004-05-14 CA CA002525909A patent/CA2525909A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003506075A (ja) * | 1999-08-05 | 2003-02-18 | エムシーエル エルエルシー | 多能性成人幹細胞およびそれを単離する方法 |
WO2001048151A1 (fr) * | 1999-12-28 | 2001-07-05 | Kyowa Hakko Kogyo Co., Ltd. | Cellules pouvant induire une differenciation dans des cellules du muscle cardiaque |
WO2002050243A2 (en) * | 2000-12-19 | 2002-06-27 | Insight Strategy And Marketing Ltd. | The use of ecm degrading enzymes for the improvement of cell transplantation |
JP2003052365A (ja) * | 2001-08-20 | 2003-02-25 | Japan Science & Technology Corp | 哺乳動物からの間葉系幹細胞の分離及びその利用方法 |
Non-Patent Citations (4)
Title |
---|
MORI Y. ET AL.: "Kotsuzui kan'yokei kansaibo", CHIRYOGAKU, vol. 35, no. 10, 2001, pages 1045 - 1048, XP002983001 * |
PELED A ET AL.: "Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4", SCIENCE, vol. 283, no. 5403, 1999, pages 845 - 848, XP002180064 * |
See also references of EP1637589A4 * |
YANIGUCHI H.: "Kan kansaibo no bunka seigyo ni yoru saisei chiryo eno approach", CHIRYOGAKU, vol. 35, no. 10, 2001, pages 1067 - 1071, XP002982800 * |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2006006692A1 (ja) * | 2004-07-08 | 2008-05-01 | 独立行政法人科学技術振興機構 | 低血清培養で選択的に増殖する動物組織遍在性の分化多能性細胞 |
WO2006123699A1 (ja) * | 2005-05-17 | 2006-11-23 | Kyowa Hakko Kogyo Co., Ltd. | 幹細胞に対する骨芽細胞への分化促進剤 |
JP2007105037A (ja) * | 2005-09-16 | 2007-04-26 | Univ Of Tokyo | キメリズムを利用した幹細胞移植のための検査 |
US20100136681A1 (en) * | 2007-04-02 | 2010-06-03 | The General Hospital Corporation | Cellular compositions for the treatment of kidney disease and uses thereof |
JP5800712B2 (ja) * | 2009-09-15 | 2015-10-28 | 株式会社 資生堂 | 真皮幹細胞の単離方法 |
US8962323B2 (en) | 2009-09-15 | 2015-02-24 | Shiseido Company, Ltd. | Method of isolating dermal stem cells |
WO2011034106A1 (ja) * | 2009-09-15 | 2011-03-24 | 株式会社資生堂 | 真皮幹細胞の単離方法 |
US11536713B2 (en) | 2009-12-25 | 2022-12-27 | Chugai Seiyaku Kabushiki Kaisha | Method for searching and screening for target of anti-cancer agent using non-human animal model having NOG established cancer cell line transplanted therein |
US11124773B2 (en) | 2010-10-06 | 2021-09-21 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell population and method for production thereof |
US11965180B2 (en) | 2010-10-06 | 2024-04-23 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell population and method for production thereof |
US10018630B2 (en) | 2011-09-07 | 2018-07-10 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell isolation |
US10934351B2 (en) | 2011-10-28 | 2021-03-02 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
US11858987B2 (en) | 2011-10-28 | 2024-01-02 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
Also Published As
Publication number | Publication date |
---|---|
EP1637589A1 (en) | 2006-03-22 |
CA2525909A1 (en) | 2004-11-25 |
JPWO2004101775A1 (ja) | 2006-07-13 |
US20070053884A1 (en) | 2007-03-08 |
EP1637589A4 (en) | 2007-01-10 |
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